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HELLP syndrome

HELLP syndrome is a life-threatening complication of pre-eclampsia. Both conditions occur during the latter stages of pregnancy, or sometimes after childbirth. more...

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HELLP is an abbreviation of the main findings:

  • Hemolytic anemia
  • Elevated Liver enzymes and
  • Low Platelet count

Signs and symptoms

Often, a patient who develops HELLP syndrome has already been followed up for gestational hypertension, or is suspected to develop pre-eclampsia (high blood pressure and proteinuria). Up to 8% of all cases present after delivery.

There is gradual but marked onset of headaches (30%), blurred vision, malaise (90%), nausea/vomiting (30%), "band pain" around the upper abdomen (65%) and tingling in the extremities. Oedema may occur but its absence does not exclude HELLP syndrome. Arterial hypertension is a diagnostic requirement, but may be mild. Rupture of the liver capsule and a resultant hematoma may occur. If the patient gets a seizure or coma, the condition has progressed into full-blown eclampsia.

Diagnosis

In a patient with possible HELLP syndrome, a batch of blood tests is performed: a full blood count, liver enzymes, renal function and electrolytes and coagulation studies. Often, fibrin degradation products (FDPs) are determined, which can be elevated. Lactate dehydrogenase is a marker of hemolysis and is elevated (>600 U/liter). Proteinuria is present but can be mild.

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TX: HELLP syndrome not timely diagnosed: both mother and fetus die after failed surgery.(Hospital Law Decisions of Note) : An article from: Hospital Law's Regan Report $5.95 HELLP syndrome leading to a diagnosis of pregnancy.(hemolysis, elevated liver enzymes, and low platelets) : An article from: Southern Medical Journal $5.95
Low plasma volume, high cholesterol predict recurrent HT. (Hellp Syndrome, Iugr, Preeclampsia). : An article from: OB GYN News $5.95 HELLP Syndrome - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References $34.95
The Silent Cries Of A HELLP Syndrome Baby $20.00 HELLP syndrome: An obstetrical multi-organ complication

HELLP Syndrome: Recognition and Perinatal Management
HELLP, a syndrome characterized by hemolysis, elevated liver enzyme levels and a low platelet count, is an obstetric complication that is frequently ...
HELLP Syndrome and Your Pregnancy
What is HELLP syndrome? HELLP syndrome is a rare but serious illness in pregnancy. This illness can start quickly, most often in the last three months ...
Low plasma volume, high cholesterol predict recurrent HT - Hellp Syndrome, Iugr, Preeclampsia
WASHINGTON - Low plasma volume and hypercholesterolemia post partum were good predictors of recurrent hypertensive disease in a subsequent pregnancy ...
Expectant management of HELLP: prednisolone cuts exacerbations
VIENNA -- Prolonged prednisolone administration reduces the risk of HELLP exacerbations in women undergoing expectant management remote from term, Pieter ...
IV Dexamethasone Speeds Recovery From HELLP
CHICAGO -- Intravenous dexamethasone provides more rapid recovery of liver function, arterial blood pressure, and urinary output in patients with prepartum ...
Systemic inflammatory response syndrome, organ failure, and outcome in critically III obstetric patients treated in an ICU - intensive care unit
Study objectives: To determine the incidence of systemic inflammatory response syndrome (SIRS) and organ failure and to describe the outcomes in critically ...
Preeclampsia presentation varies depending on race and ethnicity
RENO, NEV. -- A retrospective study examining 473 pregnancies complicated by preeclampsia has uncovered a number of significant racial and ethnic differences ...
Forensic Pathology Reviews: Volume 1
Forensic Pathology Reviews: Volume 1 Edited by Michael Tsokos, 353 pp, with tables and illus, Totowa, NJ, Humana Press, 2004. This is the first in a review ...

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