Cholestasis
In medicine, cholestasis is a condition where bile cannot from from the liver to the duodenum. more...
Etiology
- gallstones
- abdominal mass (e.g. cancer)
- primary sclerosis cholangitis, secondary to inflammatory bowel disease
- Primary biliary cirrhosis, secondary to autoimmune disorders
- congential anomalies of the bilary tract
- biliary trauma
Symptoms
- Pale stools,
- dark urine,
- itchiness (pruritis) and
- jaundice.
Bile is secreted by the liver to aid in the digestion of fats. Drugs such as golds salts,nitrofurantoin, anabolic steroids, chlorpromazine, prochlorperazine, sulindac, cimetidine, erythromycin, can cause cholestasis and may result in damage to the liver.
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