ANAL CANAL CONDYLOMA (ACC) CAN BE A DIFFICULT disease to treat and often has a high recurrence rate. In this study, researchers evaluated the possible benefits of imiquimod as adjuvant treatment for ACC. After ablation of ACC, 10 male patients received treatment with imiquimod suppositories three times weekly for 3-4 months. The imiquimod anal tampons was well tolerated and initial recurrences in some patients cleared after treatment with the imiquimod suppositories. Within a mean follow-up of 9 months no patient demonstrated recurrence of ACC. These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of ACC following ablative surgery.
Kaspari M, Kapp A, Brodersen JP. Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma. Br J Dermatol 2002 Oct; 147(4):757-9.
COPYRIGHT 2003 Journal of Drugs in Dermatology
COPYRIGHT 2003 Gale Group
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