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Landau-Kleffner syndrome

Landau-Kleffner syndrome (LKS), also called progressive epileptic aphasia, is a rare, childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram (EEG). LKS affects the parts of the brain that control comprehension and speech. The disorder usually occurs in children between the ages of 5 and 7 years. Typically, children with LKS develop normally but then lose their language skills. While many of the affected individuals have clinical seizures, some only have electrographic seizures, including electrographic status epilepticus of sleep (ESES). more...

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The syndrome can be difficult to diagnose and may be misdiagnosed as autism, pervasive developmental disorder, hearing impairment, learning disability, auditory/verbal processing disorder, attention deficit disorder, mental retardation, childhood schizophrenia, or emotional/behavioral problems.

Treatment for LKS usually consists of medications, such as anticonvulsants and corticosteroids, and speech therapy, which should be started early. A controversial treatment option involves a surgical technique called multiple subpial transection in which multiple incisions are made through the cortex of the affected part of the brain, severing the axonal tracts in the subjacent white matter.

The prognosis for children with LKS varies. Some affected children may have a permanent severe language disorder, while others may regain much of their language abilities (although it may take months or years). In some cases, remission and relapse may occur. The prognosis is improved when the onset of the disorder is after age 6 and when speech therapy is started early. Seizures generally disappear by adulthood.

Sources

  • National Institute of Neurological Disorders and Stroke (NINDS)

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ADVISORY/Prudential Financial Honors Spirit of Community Student Volunteers in Philadelphia
From Business Wire, 3/11/04

Business Editors/Education Writers

ADVISORY...for Sunday (March 21)

--(BUSINESS WIRE)

About The Prudential Spirit of Community Awards Program

The Prudential Spirit of Community Awards is a nationwide program honoring young people for outstanding acts of volunteerism. The awards program, now in its ninth year, is conducted by Prudential Financial, Inc. in partnership with the National Association of Secondary School Principals (NASSP).

More than 20,000 high school and middle level students nationwide submitted applications for this year's program. All public and private middle level and high schools in the country were eligible to nominate a student for a local Prudential Spirit of Community Award this past November. Girl Scout councils, county 4-H organizations, American Red Cross chapters, YMCAs, Camp Fire USA councils and Volunteer Centers were also eligible to nominate student volunteers for the awards program.

All local honorees were reviewed by state-level judges, who selected state honorees and distinguished finalists based on criteria such as personal initiative, creativity, effort, impact and personal growth. State honorees each will receive $1,000, an engraved silver medallion and an all-expense-paid trip in May to Washington, D.C., where they will join the top two honorees - one middle level and one high school youth - from each of the other states, the District of Columbia and Puerto Rico for several days of national recognition events. Ten of them will be named America's top youth volunteers for 2004 on May 3, 2004.

The awards are part of a broad initiative created by Prudential to encourage young people to become involved in community service. Other elements of the initiative include The Prudential Youth Leadership Institute, a community leadership training program for high school students and a variety of educational materials for young people and teachers relating to youth volunteerism.

Prudential Financial companies, with approximately $421 billion in total assets under management as of September 30, 2003, serve individual and institutional customers worldwide and include The Prudential Insurance Company of America, one of the largest life insurance companies in the U.S. These companies offer a variety of products and services, including life insurance, property and casualty insurance, mutual funds, annuities, pension and retirement related services and administration, asset management, banking and trust services, real estate brokerage franchises and relocation services. For more information, visit www.prudential.com.

Editor's Notes: Wes Somerville is the onsite event coordinator for Prudential Financial and may be reached the day of the reception via cell phone at 215-272-0132.

Prudential Financial executives are available for interview to discuss Spirit of Community and additional community outreach efforts.

Logos are immediately available upon request.

A post-event news release with photography and profiles of each of the student volunteers will be available after the honoree reception.

COPYRIGHT 2004 Business Wire
COPYRIGHT 2004 Gale Group

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