Patients usually note a deep seated mass in their soft tissue. Only when the tumor is very large do symptoms of pain or functional disturbances occur.

Retroperitoneal tumors may present with signs of weight loss and emaciation and abdominal pain. These tumors may also compress the kidney or ureter leading to kidney failure.

Incidence/Prevalence

Most frequent in middle-aged and older adults (age 40 and above), liposarcomas are the most common of all soft-tissue sarcomas. Annually 2.5 cases occur per million population.

Prognosis

The prognosis varies depending on the site of origin, the type of cancer cell, the tumor size, the depth, and proximity to lymph nodes. Metastases are common. The 5 year survival rate for a deep and high-grade liposarcoma is less than 50%.

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