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Laryngeal papillomatosis

Laryngeal papillomatosis is a rare medical condition, caused by an HPV infection of the throat. It causes assorted tumors, papillomas, to develop over a period of time. This condition obstructs the airway, and without treatment, it is potentially fatal.

Treatment

  • Traditional surgery to remove affected tissue.
  • Carbon dioxide laser surgery: "no touch" removal of affected tissue.
  • Tracheotomy: rereouting of air around the affected area.
  • Photodynamic therapy: controls tumors by using targeted dyes to irradiate any cancerous tissue.
  • Chemotherapy
  • Antibiotics
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Visualization of the hyoid bone with laryngeal endoscopy
From Ear, Nose & Throat Journal, 1/1/05 by Adam D. Rubin

A 51-year-old businessman with a history of recurrent laryngeal papillomatosis presented to our office for an evaluation. He had undergone numerous excisions and photodynamic therapy by other otolaryngologists. He was seeking an additional opinion and wished to be considered for cidofovir injection. Since his last surgery, his hoarseness had increased, but he denied any dyspnea or dysphagia.

Stroboscopic examination detected bilateral papillomatosis of the true and false vocal folds. The patient was treated with cold excision and cidofovir injection. At follow-up examinations over a period of years, he remained free of disease. However, at his most recent evaluation, we detected a "mass" on the posterior pharyngeal wall (figure). This mass turned out to be the hyoid bone, which had protruded into the pharyngeal mucosa. This finding is a normal variant and should not be mistaken for pathology.

[FIGURE OMITTED]

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COPYRIGHT 2005 Gale Group

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