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Lipodystrophy

In medicine, lipodystrophy is a condition characterized by abnormal or degenerative conditions of the body's adipose tissue. ("Lipo" is Latin for "fat" and "dystrophy" is Latin for "abnormal or degenerative condition".) more...

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Medicines

Insulin injections

A lipodystrophy can be a lump or small dent in the skin that forms when a person keeps performing injections in the same spot. These types of lipodystrophies are harmless. People who want to avoid them can do so by changing (rotating) the places where they perform injections. For diabetics, using purified insulins may also help.

Antiretroviral drugs

Other lipodystropies manifest as the excess or lack of fat in various regions of the body. These include but are not limited to having sunken cheeks, "humps" on the back or back of the neck. They are often seen as a symptom of AIDS or as side-effects from antiretroviral drugs.

Hereditary forms

Lipodystrophy can be caused by metabolic abnormalities due to genetic issues. These are often characterised by insulin resistance and are associated with Syndrome X.

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Diet linked to lipodystrophy - HIV Digest - Brief Article
From Men's Fitness, 1/1/02

Diet and alcohol have been linked to lipodystrophy, a condition marked by abnormal distribution of body fat, according to research conducted at Massachusetts General Hospital in Boston. Lipodystrophy has previously been associated with certain HIV medications and with metabolism problems developed by some people with HIV.

The report concludes that "certain modifiable components, such as fats, fiber and alcohol, are strongly associated with insulin resistance" and increased cholesterol.

Subjects who ate too much polyunsaturated fat and too little fiber had more substantial levels of insulin resistance, and those that drank more alcohol registered higher levels of LDL cholesterol. These results occurred independently of how long the patients had been taking protease inhibitors.

The study was published in the journal Clinical Infectious Diseases.

COPYRIGHT 2002 Weider Publications
COPYRIGHT 2001 Gale Group

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