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Mast cell disease

Mast cell diseases comprise a heterogeneous spectrum of diseases involving the mast cells. The most common variants are:

  • Cutaneous mastocytoma
  • Urticaria pigmentosa
  • Telangiectasia macularis eruptiva perstans (TMEP)
  • Systemic mast cell disease
  • Mast cell leukemia
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Study of mast cell precursors
From Journal of Drugs in Dermatology, 11/1/04

This study is currently recruiting patients.

Sponsored by National Institute of Allergy and Infectious Diseases (NIAID)

This study will investigate mast cell precursors that circulate in the blood. In a group of diseases collectively known as mastocytosis, mast cells accumulate in abnormal amounts in the skin, lymphoid tissues, bone marrow, liver, and spleen. Some forms of mastocytosis have a generally good prognosis; for others, the prognosis is poorer. There is no known cure for any form of the disease. A better understanding of mast cells and how they respond to certain substances may provide insights that will lead to effective treatments for mastocytosis.

Study ID Numbers: 980027; 98-I-0027

ClinicalTrials.gov Identifier: NCT00001756

COPYRIGHT 2004 Journal of Drugs in Dermatology, Inc.
COPYRIGHT 2005 Gale Group

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