Find information on thousands of medical conditions and prescription drugs.

McCune-Albright syndrome

McCune-Albright syndrome, described in 1937 by McCune and Albright, is a disease where two of the three following features are present:

  • (autonomous) endocrine hyperfunction
  • Fibrous dysplasia
  • CafĂ©-au-lait spots


The endocrine aspect of the disease can manifest itself as extremely premature puberty.

Genetically, there is a post-zygotic mutation of a gene involved in G-protein signalling, preventing downregulation of cAMP signalling.

Home
Diseases
A
B
C
D
E
F
G
H
I
J
K
L
M
Mac Ardle disease
Macroglobulinemia
Macular degeneration
Mad cow disease
Maghazaji syndrome
Mal de debarquement
Malaria
Malignant hyperthermia
Mallory-Weiss syndrome
Malouf syndrome
Mannosidosis
Marburg fever
Marfan syndrome
MASA syndrome
Mast cell disease
Mastigophobia
Mastocytosis
Mastoiditis
MAT deficiency
Maturity onset diabetes...
McArdle disease
McCune-Albright syndrome
Measles
Mediterranean fever
Megaloblastic anemia
MELAS
Meleda Disease
Melioidosis
Melkersson-Rosenthal...
Melophobia
Meniere's disease
Meningioma
Meningitis
Mental retardation
Mercury (element)
Mesothelioma
Metabolic acidosis
Metabolic disorder
Metachondromatosis
Methylmalonic acidemia
Microcephaly
Microphobia
Microphthalmia
Microscopic polyangiitis
Microsporidiosis
Microtia, meatal atresia...
Migraine
Miller-Dieker syndrome
Mitochondrial Diseases
Mitochondrial...
Mitral valve prolapse
Mobius syndrome
MODY syndrome
Moebius syndrome
Molluscum contagiosum
MOMO syndrome
Mondini Dysplasia
Mondor's disease
Monoclonal gammopathy of...
Morquio syndrome
Motor neuron disease
Motorphobia
Moyamoya disease
MPO deficiency
MR
Mucopolysaccharidosis
Mucopolysaccharidosis...
Mullerian agenesis
Multiple chemical...
Multiple endocrine...
Multiple hereditary...
Multiple myeloma
Multiple organ failure
Multiple sclerosis
Multiple system atrophy
Mumps
Muscular dystrophy
Myalgic encephalomyelitis
Myasthenia gravis
Mycetoma
Mycophobia
Mycosis fungoides
Myelitis
Myelodysplasia
Myelodysplastic syndromes
Myelofibrosis
Myeloperoxidase deficiency
Myoadenylate deaminase...
Myocarditis
Myoclonus
Myoglobinuria
Myopathy
Myopia
Myositis
Myositis ossificans
Myxedema
Myxozoa
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Medicines

Read more at Wikipedia.org


[List your site here Free!]


CME test
From Ear, Nose & Throat Journal, 10/1/05

Sponsored by the University of Nebraska Medical Center, Center for Continuing Education

To obtain CME credits, complete the test below, following these guidelines:

1. Read each article carefully.

2. Choose the most appropriate response to each of the following questions and record these on the registration form. Unanswered questions are considered incorrect.

3. Send the completed registration form and your payment (check, money order, VISA, MasterCard, American Express) to the Center for Continuing Education, University of Nebraska Medical Center (UNMC).

4. After your test has been graded, you will receive a receipt, a copy of the correct answers, and a credit statement certifying completion from the UNMC. Questions about the test should be addressed to UNMC Center for Continuing Education (402-559-4152).

Credit: The University of Nebraska Medical Center, Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Nebraska Medical Center, Center for Continuing Education designates this educational activity for a maximum of 3 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

This CME activity was planned and produced in accordance with the ACCME Essentials.

1. Chan, in this month's Imaging Clinic, states that McCune-Albright syndrome is included in which type of fibrous dysplasia?

a. type I

b. type II

c. type III

d. type IV

2. According to Mamak et al, sudden hearing loss is defined as a sensorineural hypoacusis of at least 30 dB in 3 consecutive speech frequencies that has occurred within the previous 5 days.

True or False

3. With which of the following statements regarding sudden hearing loss would Mamak and colleagues agree?

a. Its etiopathogenesis has been well defined.

b. Most cases are idiopathic.

c. Vertigo is present in as many as 60% of cases.

d. Approximately 80% of cases are unilateral.

4. According to Thompson (Pathology Clinic), which of the following statements regarding parathyroiditis is false?

a. It is rare and poorly understood.

b. Most patients with this condition are asymptomatic.

c. It is characterized by a slightly enlarged gland.

d. Antibodies to parathyroid tissue are seen in most cases.

5. Amin et al state that most eases of nasal glioma that have been reported in the literature have occurred in:

a. elderly patients

b. middle-aged adults

c. infants

d. young adults

6. Nasal glioma is malignant, as evidenced by the presence of microscopic abnormalities, according to Amin et al.

True or False

7. Which of the following is considered a rare complication of tonsillectomy, according to Patel and Brookes?

a. cardiac arrhythmia

b. pneumomediastinum

c. hemorrhage

d. aspiration of blood

8. The patient Patel and Brookes describe in their case report developed subcutaneous emphysema after undergoing a tonsillectomy as a result of his:

a. repeated sneezing

b. repeated coughing

c. repeated nose blowing

d. repeated performance of Valsalva's maneuver

COPYRIGHT 2005 Medquest Communications, LLC
COPYRIGHT 2006 Gale Group

Return to McCune-Albright syndrome
Home Contact Resources Exchange Links ebay