Pleural effusion Chest x-ray of a pleural effusion. The arrow A shows fluid layering in the right pleural cavity. The B arrow shows the width of the lung
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Pleural effusion

Pleural effusion is a medical condition where fluid accumulates in the pleural cavity which surrounds the lungs, making it hard to breathe. more...

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Four main types of fluids can accumulate in the pleural space:

  • Serous fluid (hydrothorax)
  • Blood (hemothorax)
  • Lipid (chylothorax)
  • Pus (pyothorax or empyema)

Causes

Pleural effusion can result from reasons such as:

  • Cancer, including lung cancer or breast cancer
  • Infection such as pneumonia or tuberculosis
  • Autoimmune disease such as lupus erythematosus
  • Heart failure
  • Bleeding, often due to chest trauma (hemothorax)
  • Low oncotic pressure of the blood plasma
  • lymphatic obstruction
  • Accidental infusion of fluids

Congestive heart failure, bacterial pneumonia and lung cancer constitute the vast majority of causes in the developed countries, although tuberculosis is a common cause in the developing world.

Diagnosis

In states of excess accumulation, pleural fluid can be sampled and evaluated to determine what disease state may be causing it. This can be sampled through a thoracentesis, where a needle is inserted through the back of the chest wall and into the pleural space. The evaluation consists of:

  1. Gram stain and culture - identifies bacterial infections
  2. Cell count and differential - differentiates exudative from transudative effusions
  3. Cytology - identifies cancer cells, may also identify some infective organisms
  4. Chemical composition including protein, lactate dehydrogenase, amylase, pH and glucose - differentiates exudative from transudative effusions
  5. Other tests as suggested by the clinical situation - lipids, fungal culture, viral culture, specific immunoglobulins

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Thoracoscopy and placement of an indwelling catheter for the management of malignant pleural effusion: a day case
From CHEST, 10/1/05 by Ahmed Al- S. Halfawy

PURPOSE: The purpose of this study was to evaluate the possibility of performing diagnostic thoracoscopy for patients with pleural effusions and inserting an indwelling catheter at the end of the procedure when intrapleural pathology was identifiable as possible malignancy, and discharging those patients on the same day of the procedure on domiciliary self drainage.

METHODS: Diagnostic thoracoscopy was performed under local anesthesia and conscious sedation, when a lesion was observed and judged to be the possible cause of the effusion and when it was thought that it was most probably malignant, a second skin incision was made 5 cm dorsal to the first incision. An indwelling catheter was tunnelled under the skin with the outer part of the catheter with the valve at its end coming out from the first incision. The fenestrated end was inserted into the pleural cavity through the second incision. Through the first incision, an intercostal tube was also placed. When patients recovered, they were asked to cough repeatedly until air stopped bubbling in the underwater seal. The intercostal tube was then removed and the indwelling catheter connected to surgivac pump to produce continuous negative pressure.

RESULTS: This technique was performed in eight patients with malignant pleural effusions who were diagnosed during thoracoscopy, all patients were discharged on the same day of the procedure, the intercostal tube was removed after a short period that ranged from 1 to 12 hours.

CONCLUSION: It is possible to minimize hospital stay after thoracoscopy for malignant pleural effusions by inserting an indwelling catheter to complete the draining of the effusion on an outpatient basis.

CLINICAL IMPLICATIONS: Patients with malignant pleural effusions can undergo thoracoscopy and be discharged home on the same day. This technique also abolished the need for chemical pleurodesis as the indwelling catheter have a comparable success rate in producing spontaneous pleurodesis.

DISCLOSURE: Ahmed Al-Halfawy, Product/procedure/technique that is considered research and is NOT yet approved for any purpose, placement of an indwelling pleural catheter at the same sitting of thoracoscopy for malignant pleural effusiosns and discharging the patient on the same day of the procedure.

Ahmed S. Al-Halfawy MD * Faculty of Medicine, Cairo University, Cairo, Egypt

COPYRIGHT 2005 American College of Chest Physicians
COPYRIGHT 2005 Gale Group

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