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Post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) is a term for certain psychological consequences of exposure to, or confrontation with, stressful experiences that the person experiences as highly traumatic. These experiences can involve actual or threatened death, serious physical injury, or a threat to physical and/or psychological integrity. It is occasionally called post-traumatic stress reaction to emphasize that it is a routine result of traumatic experience rather than a manifestation of a pre-existing psychological weakness on the part of the patient. more...

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Symptoms can include the following: Nightmares, flashbacks, emotional detachment or numbing of feelings (emotional self-mortification or dissociation), insomnia, avoidance of reminders and extreme distress when exposed to the reminders ("triggers"), irritability, hypervigilance, and and excesive startle response.

Experiences likely to induce the condition include:

  • childhood physical/emotional or sexual abuse
  • adult experiences of rape, war and combat exposure
  • violent attacks
  • natural catastrophes
  • life-threatening childbirth complications

For most people, the emotional effects of traumatic events will tend to subside after several months. If they last longer, then diagnosing a psychiatric disorder is generally advised. Most people who experience traumatic events will not develop PTSD. PTSD is thought to be primarily an anxiety disorder, and should not be confused with normal grief and adjustment after traumatic events. There is also the possibility of simultaneous suffering of other psychiatric disorders (i.e. comorbidity). These disorders often include major depression or general anxiety disorder


PTSD may have a "delayed onset" of years, or even decades, and may even be triggered by a specific body movement if the trauma was stored in the procedural memory, by another stressful event, such as the death of a family member or someone else close, or by the diagnosis of a life-threatening medical condition.

Also, doctors have conducted clinical studies indicating traumatized children with PTSD are more likely to later engage in criminal activities than those who do not have PTSD.

Background

Psychological distress after trauma was reported in 1900 BC by an Egyptian physician who described hysterical reactions to trauma (Veith 1965). Hysteria was also related to "traumatic reminiscences" a century ago (Janet 1901). At that time, Sigmund Freud's pupil, Kardiner, was the first to describe what later became post-traumatic stress disorder symptoms (Lamprecht & Sack 2002).

Hippocrates utilized a homeostasis theory to explain illness, and stress is often defined as the reaction to a situation that threatens the balance or homeostasis of a system (Antonovsky 1981). The situation causing the stress reaction is defined as the "stressor", but the stress reaction, and not the stressor is what jeopardizes the homeostasis (Aardal-Eriksson 2002). Post-traumatic stress can thus be seen as a chemical imbalance of neurotransmitters, according to stress theory.

However, PTSD per se is a relatively recent diagnosis in psychiatric nosology, first appearing in the Diagnostic and Statistical Manual of Mental Disorders (DSM) in 1980. It is said development of the PTSD concept partly has socio-economic and political implications (Mezey & Robbins 2001). War veterans were to a great deal incapacitated by psychiatric illness, including post-traumatic stress in the aftermath of the Vietnam War. However, they had difficulties receiving economic compensation since there was no psychiatric diagnosis available by which veterans could claim indemnity. This situation has changed, and PTSD is now one of several psychiatric diagnoses for which a veteran can receive compensation, such as a war veteran indemnity pension, in the US (Mezey & Robbins 2001). While PTSD-like symptoms were recognized in combat veterans following many historical conflicts, the modern understanding of the condition dates to the 1980s.

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Screening patients for post-traumatic stress disorder
From American Family Physician, 8/1/05 by Anne D. Walling

Significant trauma is increasingly common in the general population, and an estimated one in four of those exposed to life-threatening situations develops post-traumatic stress disorder (PTSD). Without treatment, PTSD causes symptoms for more than five years in the majority of cases, and may bring about additional psychiatric morbidity such as depression. The highest rates of PTSD follow sexual assault, but many women are not diagnosed and treated. An estimated 73 percent of women who have been raped or assaulted seek medical care in the year following the attack, whereas only 19 percent seek psychologic help. If patients with PTSD could be identified and treated, significant morbidity could be avoided. Meltzer-Brody and colleagues developed and tested a screening instrument for PTSD, targeting women who attended a gynecology clinic.

The researchers offered screening to all 292 women who attended the clinic for routine annual examination between June 2001 and March 2002. Patients completed a comprehensive health survey that included questions about significant trauma. Those who reported a traumatic event were asked to complete a four-item screening survey known as SPAN (Startle, Physiological arousal, Anger, and emotional Numbness), named for the four major symptoms of PTSD. The screening performance of the SPAN questionnaire was compared with full psychiatric assessment, including a structured interview designed to detect PTSD.

Of the 292 participants, 46 percent were single, 49 percent were black, and 43 percent were white. The mean age was 34 ([+ or -] 12) years. Significant traumatic events were reported by 88 (30 percent) of the women; of these, 32 women agreed to full psychiatric assessment, and 56 declined. There were no significant differences in variables between the two groups. The main reasons given for nonparticipation were lack of time and inability to return to the clinic. Interviews identified criteria for one or more psychiatric diagnoses in 31 of 32 women. Twenty-five women (78 percent) met criteria for PTSD, but only three of these were receiving any form of psychiatric treatment. Other diagnoses included major depression (62 percent), panic disorder (28 percent), social phobia (28 percent), generalized anxiety disorder (19 percent), and substance abuse (15 percent).

The authors calculate that the single question about experiencing significant trauma had a positive predictive value of 78 percent for PTSD in the study population. The SPAN instrument had a sensitivity of 72 percent and a specificity of 71 percent using a cutoff score of 5. These findings equate to a positive likelihood ratio of 2.52 and a negative likelihood ratio of 0.39.

As in other studies, one third of women reported experiencing significant trauma; however, the proportion who developed clinical PTSD was much higher than expected. This could be because of selection bias in the women who agreed to take part in the study. Nevertheless, the authors conclude that asking about trauma and following up with the SPAN questionnaire can effectively identify which women to refer for more intensive psychiatric assessment and treatment.

Meltzer-Brody S, et al. A brief screening instrument to detect posttraumatic stress disorder in outpatient gynecology. Obstet Gynecol October 2004;104:770-6.

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COPYRIGHT 2005 American Academy of Family Physicians
COPYRIGHT 2005 Gale Group

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