Lactuca virosa is a legal ethnobotanical in the United States. It is related to common lettuce (L. sativa), and is often called Wild Lettuce, Opium Lettuce, Laitue vireuse, Poisonous Lettuce, or Rakutu-Karyumu-So. more...
L. virosa was used in the 19th century by physicians when opium could not be obtained. It was studied extensively by the Council of the Pharmaceutical Society of Great Britain in 1911 . They discovered two chemicals responsible for the properties of L. virosa; lactucopicrin and lactucin. In the United States, the plant experienced a resurgence in popularity in the 1970s. Today the plant is un-scheduled by the FDA, meaning it is legal to grow, purchase and own without prescription or license.
The effects of ingesting L. virosa are similar to opium, although no opiates are present in the plant. Effects are felt quickly but do not last long, between half an hour to a couple of hours. The plant has been used as an anesthetic and a sleep aid, as well as recreationally. Oils and extracts can be produced from L. virosa, they are often added to tea to help induce sleep. Many add the greens to salads, though the leaves of L. virosa are more bitter than other salad greens. Smoking involves either dried leaves or a sticky precipitate extracted from the leaves. Beverages can be prepared by soaking the leaves in alcohol.
The plant contains flavonoids, which have strong anti-oxidant properties. L. virosa has also been found to contain coumarins, and N-methyl-β-phenethylamine .
Read more at Wikipedia.org