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Labetalol

Labetalol hydrocholoride (Normodyne®, Trandate®, fixed combination with hydrochlorothiazide: Normozyde®) is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output. more...

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Administration

Labetalol is available in 100, 200, and 300 mg tablets and for intravenously (only as Trandate®) in 5 mg/ml. Adults taking tablets usually start with 100 mg two times a day, with a maximum of 2.4 g/day. In an emergency situation, this may be higher. By IV, the patient is usually started at 2 mg/minute or 20 mg, with a maximum of 300 mg.

Side effects

Side effects may include:

  • Drowsiness
  • Fatigue
  • Weakness
  • Difficulty sleeping
  • Diminished sexual function
  • Scalp tingling which passes after time.

Read more at Wikipedia.org


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Able Labs submits ANDA for Labetalol OK - Statistical Data Included
From Drug Store News, 3/16/98

DynaGen Inc.'s Able Laboratories Inc. has submitted an abbreviated new drug application to the FDA seeking approval for its generic Labetalol hydrochloride tablets. Sales of Labetalol hydrochloride tablets, marketed by Schering-Plough Corp. and Glaxo Wellcome PLC under the brand names Normodyne and Trandate, respectively, were about $80 million in 1996, according to DynaGen.

COPYRIGHT 1998 Lebhar-Friedman, Inc.
COPYRIGHT 2000 Gale Group

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