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Latanoprost

Latanoprost (pronounced la-TA-noe-prost) opthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes. It is also known by the brand name of Xalatan Op. more...

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Molecular formula: C26H40O5

Possible side effects:

  • May cause blurred vision;
  • May cause eyelid redness;
  • May permanently darken eyelashes;
  • May cause eye discomfort;
  • May eventually cause permanent darkening of the iris to brown (heterochromia);
  • May cause a temporary burning sensation during use.
  • May cause thickening of the eyelashes.

Read more at Wikipedia.org


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Latanoprost is a selective FP prostanoid receptor agonist used in the treatment of glaucoma which also has a hypertrichotic side effect - Washington Whispers
From Journal of Drugs in Dermatology, 12/1/02

In this study, the effects of latanoprost on hair growth were evaluated in macaque monkeys that are models of androgenetic alopecia (AGA). 8 monkeys were divided into two groups: one group received a daily topical application of 50microg/ml of latanoprost for 5 months, and the control group had a daily application of vehicle. For an additional 3 months, 2 monkeys from each group were given 500microg/ml latanoprost, while the remaining monkeys continued with the previous treatment. Hair regrowth was evaluated by monthly photographs and phototrichographic analysis. Fifty microg/ml of latanoprost caused minimal hair regrowth whereas 500microg/ml induced moderate to marked hair regrowth with 5-10% conversion of vellus hairs to intermediary or terminal hairs. The vehicle group showed no effect. Further studies this agent can be used in humans. However, this research suggests possible new agents will be available for AGA.

Uno H, Zimbric ML, Albert DM, Stjernscbantz J. Effect of latanoprost on hair growth in the bald scalp of the stump-tailed macacque: a pilot study. Acta Derm Venereol 2002; 82(1):7-12.

COPYRIGHT 2002 Journal of Drugs in Dermatology
COPYRIGHT 2003 Gale Group

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