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Lotensin

Benazepril hydrochloride, brand name Lotensin®, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor. more...

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Dosage forms

Oral tablets, 5 mg, 10 mg, 20 mg, and 40 mg

Side effects

Most commonly, headache and cough. Anaphylaxis and angioedema can occur. Hyperkalemia, or an elevation of potassium levels, can also occur.

Benazepril may cause harm to the fetus during pregnancy.

Contraindications

Benazepril should be discontinued during pregnancy.

Benazepril hydrochloride, brand name Fortekor®, is a medication used to treat congestive heart failure in dogs congestive heart failure, and chronic renal failure in cats.

Fortekor is marketed by Novartis.

Read more at Wikipedia.org


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Andrx Launches Its Generic Versions of Lotensin and Lotensin HCT
From Business Wire, 2/11/04

Business Editors/Health/Medical Writers

FORT LAUDERDALE, Fla.--(BUSINESS WIRE)--Feb. 11, 2004

Andrx Corporation (Nasdaq:ADRX) ("Andrx") today announced that the United States Food and Drug Administration has approved its Abbreviated New Drug Applications for its bioequivalent versions of Lotensin(R) (Benazepril Hydrochloride Tablets, 5 mg, 10 mg, 20 mg, and 40 mg) and Lotensin HCT(R) (Benazepril Hydrochloride and Hydrocholorthiazide Tablets, 5 mg/6.25 mg, 10 mg/12.5 mg, 20 mg/12.5 mg, and 20 mg/25 mg). According to Novartis, which sells these brands, these products had 2003 sales of $335 million and $81 million, respectively. Andrx has already commenced shipping its generic versions of Lotensin and Lotensin HCT.

About Andrx Corporation

Andrx Corporation develops and commercializes: bioequivalent versions of controlled-release brand name pharmaceuticals, using its proprietary drug delivery technologies; bioequivalent versions of specialty, niche and immediate-release pharmaceutical products, including oral contraceptives; and brand name or proprietary controlled-release formulations of existing immediate-release or controlled-release drugs where it believes the application of Andrx's drug delivery technologies may improve the efficacy or other characteristics of those products. Andrx also has distribution operations, which purchase primarily generic pharmaceuticals manufactured by third parties and sell them primarily to independent pharmacies, pharmacy chains, pharmacy buying groups and, to a lesser extent, physicians' offices.

Forward-looking statements (statements which are not historical facts) in this release are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. For this purpose, any statements contained herein or which are otherwise made by or on behalf of the Company that are not statements of historical fact may be deemed to be forward-looking statements. Without limiting the generality of the foregoing, words such as "may," "will," "to," "plan," "expect," "believe," "anticipate," "intend," "could," "would," "estimate," or "continue" or the negative other variations thereof or comparable terminology are intended to identify forward-looking statements. Investors are cautioned that all forward-looking statements involve risk and uncertainties, including but not limited to, the Company's dependence on a relatively small number of products, licensing revenues, the timing and outcome of litigation, the commercial success of product launches, including its generic Lotensin and generic Lotensin HCT, government regulation, competition, and manufacturing results. Andrx Corporation is also subject to other risks detailed herein or detailed from time to time in its filings with the U.S. Securities and Exchange Commission. Andrx disclaims any responsibility to update the statements contained herein.

This release and additional information about Andrx Corporation are also available on the Internet at: http://www.andrx.com.

COPYRIGHT 2004 Business Wire
COPYRIGHT 2004 Gale Group

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