Molecular structure of ranitidine
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Zantac

Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). It is currently marketed by GlaxoSmithKline under the trade name Zantac. more...

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Clinical use

Certain preparations of ranitidine are available over the counter (OTC) in various countries. In the United States, 75 mg and 150 mg tablets are available OTC. In Australia, small packs of 150 mg and 300 mg tablets are Schedule 2 Pharmacy Medicines. Larger doses and pack sizes still require a prescription.

Outside of the United States, ranitidine is combined with bismuth (which acts as a mild antibiotic) as a citrate salt (ranitidine bismuth citrate, TritecĀ®), to treat Helicobacter pylori infections. This combination is usually given with clarithromycin, another antibiotic.


Ranitidine Brand Names Around The World

Acidex (Argentina) Aciloc (India) Acloral (Mexico) Acran (Indonesia) Aldin (India) Anistal (Mexico) Antagonin (Benin, Burkina-Faso, Ethiopia, Gambia, Ghana, Guinea, Ivory-Coast, Kenya, Liberia, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Senegal, Seychelles, Sierra-Leone, Sudan, Tanzania, Tunia, Uganda, Zambia, Zimbabwe) Apo-Ranitidine (Canada, New-Zealand) Atural (Peru) Ausran (Australia) Avintac (Mexico) Axoban (Japan) Azantac (France,Mexico) Consec (India) Coralen (Spain) Duractin (Korea) Eltidine (Korea) Ezopta (Greece) Galidrin (Mexico) Gastrial (Argentina) Gastridin (Indonesia) Gastrosedol (Argentina) Hexer (Indonesia) Histac (Benin, Burkina-Faso, Ethiopia, Gambia, Ghana, Guinea, Ivory-Coast, Kenya, Liberia, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Senegal, Seychelles, Sierra-Leone, Sudan, Tanzania, Tunia, Uganda, Zambia, Zimbabwe, India, Thailand) Histak (South-Africa) Iqfadina (Mexico) Juradine (Korea) Kemoranin (Indonesia) Lydin (India) Microtid (Mexico) Neoceptin-R (Benin, Burkina-Faso, Ethiopia, Gambia, Ghana, Guinea, Ivory-Coast, Kenya, Liberia, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Senegal, Seychelles, Sierra-Leone, Sudan, Tanzania, Tunia, Uganda, Zambia, Zimbabwe) Novo-ranidine (Hong-Kong) Pilorex (Peru) Ponaltin (Korea) Ptinolin (Greece) Quantor (Spain) Quicran (Taiwan) Radinat (Ecuador) Ranacid (Norway) Randin (Bahrain, Cyprus, Egypt, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Oman, Qatar, Republic-of-Yemen, Saudi-Arabia, Syria, United-Arab-Emirates) Rani 2 (Australia) Ranial (India) Raniben (Italy) Ranidil (Italy) Ranidine (Thailand) Ranihexal (Australia) Ranimex (Finland) Ranin (Indonesia) Raniogas (Colombia) Raniplex (France) Ranisen (Mexico) Ranisul (Colombia) Ranitab (Philippines) Ranital (Slovenia) Ranitax (Peru) Ranix (Philippines) Ranolta (Hong-Kong) Rantac (India) Rantacid (Finland) Rantin (Indonesia, Korea) Ratic (Thailand) Raticina (Argentina) R-Loc (Benin, Burkina-Faso, Ethiopia, Gambia, Ghana, Guinea, Ivory-Coast, Kenya, Liberia, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Senegal, Seychelles, Sierra-Leone, Sudan, Tanzania, Tunia, Uganda, Zambia, Zimbabwe) Rolan (Bahrain, Cyprus, Egypt, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Oman, Qatar, Republic-of-Yemen, Saudi-Arabia, Syria, United-Arab-Emirates) Rosimol (Argentina) RND (Taiwan) Simetac (Hong-Kong) Sostril (Germany) Taural (Argentina, Costa-Rica, Dominican-Republic, El-Salvador, Guatemala, Honduras, Nicaragua, Panama, Ecuador) Terodul (Mexico) Ul-Pep (Colombia) Ulcaid (South-Africa) Ulceran (Peru) Ulceranin (Indonesia) Ulcex (Italy) Ulcin (Philippines) Ulcirex (France) Ulsal (Austria) Ultak (South-Africa) Urantac (Korea) Verlost (Greece) Vesyca (Taiwan) Vizerul (Argentina) Weichilin (Taiwan) Weidos (Taiwan) Xanidine (Thailand) Zantab (Israel) Zantac (US) Zantac FR (Philippines) Zantadin (Indonesia) Zantic (Germany, Switzerland) Zidac (France) Zinetac (India)

Read more at Wikipedia.org


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Glaxo Wellcome claims pace of Zantac competition is stable - Statistical Data Included
From Drug Store News, 3/16/98

According to Glaxo Wellcome, the pace of market share captured by generic versions of its anti-ulcer drug Zantac has stabilized since the first of the year. The company predicts Zantac could lose up to 80 percent market share within 12 months. Full generic competition for Zantac began in September.

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