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Zelnorm

Tegaserod is a 5-HT4 agonist used for the management of constipation-predominant irritable bowel syndrome (IBS). It is currently marketed by Novartis under the trade names Zelnorm (in the US) or Zelmac (in other countries).

Tegaserod is a motility stimulant. Therapeutic effect is achieved through activation of 5-HT4 receptors of the enteric nervous system in the gastrointestinal tract. Tegaserod stimulates gastrointestinal motility and the peristaltic reflex, and possibly also reduces abdominal pain (Rossi, 2004).

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New evidence-based guideline targets treatment of irritable bowel syndrome. (Diagnostic Work-Up Simplified). : An article from: Family Practice News $5.95 Guidelines for IBS would streamline diagnostic testing: Zelnorm and Lotronex get 'grade a' status for data showing high efficacy, tolerability. (First ... : An article from: Internal Medicine News $5.95
New and approved: Zelnorm * Xyrem. (Rx).(irritable bowel syndrome) : An article from: Family Practice News $5.95 Zelnorm, Cymbalta.(New & Approved) : An article from: Skin & Allergy News $5.95
New & approved: Zelnorm * Xyrem. : An article from: Internal Medicine News $5.95 Zelnorm.(NEW & APPROVED) : An article from: Internal Medicine News $5.95

FDA panel recommendation: Zelnorm considered as constipation Tx
ROCKVILLE, MD. -- A federal advisory panel has recommended approval of the irritable bowel syndrome drug tegaserod as a treatment for primary chronic ...
From OB/GYN News, 8/15/04 by Elizabeth Mechcatie
New risk information on IBS drug Zelnorm
To ensure that women and health professionals have me most current and complete information available when taking or prescribing Zelnorm (tegaserod maleate) for short-term treatment of irritable bo
From FDA Consumer, 7/1/04
Zelnorm: new warnings for IBS drug
Novartis Pharmaceuticals Corp. has changed the professional labeling of Zelnorm (tegaserod maleate) to include new warnings about diarrhea, ischemic ...
From OB/GYN News, 6/15/04 by Kerri Wachter
Tegaserod for irritable bowel syndrome - Zelnorm - STEPS
Synopsis: Tegaserod (Zelnorm) is the first treatment approved by the U.S. Food and Drug Administration (FDA) for the short-term management of constipation-predominant ...
From American Family Physician, 1/15/04 by G. Robert DeYoung
Zelnorm - New & Approved
(tegaserod maleate, Novartis) A serotonin-4 receptor (5-[HT.sub.4]) agonist for short-term treatment of women with constipation-predominant irritable ...
From OB/GYN News, 9/15/02 by Elizabeth Mechcatie
Irritable bowel syndrome
A GROWING NUMBER of African-Americans--especially women--are being diagnosed with the gastrointestinal disorder known as irritable bowel syndrome (IBS).
From Ebony, 7/1/05
Drugs, pregnancy, and lactation: GI agents: part I
Gastrointestinal complaints are common in pregnancy and the postpartum period. They include conditions such as nausea and vomiting, constipation, diarrhea, ...
From OB/GYN News, 11/15/05 by Gerald G. Briggs
Guideline for chronic constipation management
American College of Gastroenterology Chronic Constipation Task Force. An evidence-based approach to the management of chronic constipation in North America. Am J Gastroenterol 2005; 100:S1-S4. *
From Journal of Family Practice, 11/1/05

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