Image:Ethosuximide.gif

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Zarontin

Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures. It is sold by Pfizer under the name Zarontin®. more...

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Zoledronic acid

Zyvox

Adverse Effects

Central Nervous System

Common

drowsiness
mental confusion
insomnia
nervousness
headache
euphoria
ataxia
hiccups
impaired concentration
irritability
hyperactivity
loss of taste
night terrors

Rare

paranoid psychosis
increased libido
exacerbation of depression

Gastrointestinal

dyspepsia
vomiting
nausea
cramps
constipation
diarrhea
stomach pain
loss of appetite
weight loss
gingival hyperplasia
swelling of tongue

Genitourinary

microscopic hematuria
vaginal bleeding

Hematopoietic

The following can occur with or without bone marrow loss:

pancytopenia
agranulocytosis
leukopenia
eosinophilia

Integumentary

urticaria
systemic lupus erythematosus
Stevens-Johnson syndrome
hirsutism
pruritic erythematous rashes

Ocular

myopia

Complications

abnormal liver function

Drug Interactions

Valproates can either decrease or increase the levels of ethosuximide; However, combinations of valproates and ethosuximide had a greater Protective Index than either drug alone.

It may elevate serum phenytoin levels.

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