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Norplant

Norplant is a form of birth control released in 1991 by Wyeth Pharmaceuticals, consisting of a set of six small, silicone capsules filled with levonorgestrel, a synthetic progestin used in many birth control pills. In 2002, Norplant was discontinued from production; limited supplies still remained until 2004. A similar product, featuring two rods instead of six, called Jadelle, is approved for US use but is not yet commercially manufactured in the United States. more...

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Insertion

Norplant is implanted under the skin in the upper arm of a woman, by creating a small incision and inserting the capsules in a fanlike shape. Insertion of Norplant usually takes 15 minutes and the capsules can sometimes be seen under the skin, although usually they look like small veins. They can also be felt under the skin. Once inserted, the contraceptive works within 24 hours and lasts up to five years.

Function and effectiveness

Norplant works by preventing ovulation, which means that no eggs are released for fertilization; by thickening the mucus of the uterus, which prevents sperm from entering; and by thinning the lining of the uterus, which makes implementation of an egg less likely. A small amount of the hormone is released through the capsules continuously, more during the first year and a half, but then at a level similar to most contraceptive pills afterward. According to studies completed, Norplant has been shown to be 99% – 99.95% effective at preventing pregnancy, and is one of the most reliable, though not the most available, forms of birth control around. It is important that women understand Norplant, however, does not protect against sexually transmitted diseases.

Contraindications

Norplant should not be used in women with liver disease, breast cancer, or blood clots. Women who believe they may already be pregnant or those with vaginal bleeding should first see a physician. However, since Norplant does not contain estrogen like some birth control pills, older women, women who smoke, and women with high blood pressure are not restricted from using the system.

Side effects

After three months of using Norplant, women will need to schedule a follow-up appointment to monitor blood pressure and discuss any concerns. Side effects may include irregular menstrual periods for the first approximately three months, including periods lasting longer than normal, bleeding or spotting between periods, or going with no period for the mentioned period of time. These changes are not serious. Less common side effects include weight gain or loss, headache, depression, acne, or excessive hair growth. Sometimes, mild pain or itching at the site of the implant will occur. Ovarian cysts may also occur, but usually do not require treatment.

Removal

Norplant can be removed with only minor inconvenience at any time by creating a second incision and withdrawing the capsules. Norplant is normally removed when the five year period is over and reinsertion of a new set is preferred, or if:

  • Pregnancy is desired
  • Differing birth control is preferred
  • Complications arise

Read more at Wikipedia.org


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Advisory for Norplant contraceptive kits - Updates - Brief Article
From FDA Consumer, 9/1/02

In July, Wyeth Pharmaceuticals of Madison, N.J., announced that due to limitations in product component supplies, the company will no longer distribute the six-capsule Norplant System (levonorgestrel implants). The Norplant capsules are implanted under the skin of the upper arm and provide contraception for five years.

The FDA advises that women using the system contact their doctors about other contraceptive options to use after the five-year expiration date of their Norplant system. For women who prefer to have the Norplant capsules removed, Wyeth will pay for removal until December 31, 2002.

Wyeth also announced that women with Norplant capsules from certain lots may now safely stop using backup contraception. Previously, these women were advised to use backup contraception because of concerns about lower than expected release of the hormone levonorgestrel from several lots. Testing of the specified lots has not shown the effectiveness of the implants to be different from that seen in clinical trials and described in product labeling.

Norplant users who depend on condoms for protection against sexually transmitted diseases should continue to use them.

For more information, contact the Norplant System Information Line at 1-800-364-9809.

COPYRIGHT 2002 U.S. Government Printing Office
COPYRIGHT 2004 Gale Group

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