Structural formula of enflurane
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Enflurane

Enflurane (2-chloro-1,1,2,-trifluoroethyl-difluomethyl ether)is a halogenated ether that was commonly used for inhalational anesthesia during the 1970s and 1980s. Developed by Ross Terrell in 1963, it was first used clinically in 1966. more...

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Enflurane is a structural isomer of isoflurane. It vaporizes readily, but is a liquid at room temperature.

Clinically, enflurane produces a dose-related depression of myocardial contractility with an associated decrease in myocardial oxygen consumption. Between 2% and 5% of the inhaled dose is oxidised in the liver, producing fluoride ions and difluoromethoxy-difluoroacetic acid. This is significantly higher than the metabolism of its structural isomer isoflurane.

Physical properties

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Enflurane (Ethrane): A compendium and reference Enflurane: Selected proceedings of the sixth European Congress of Anaesthesiology, London, September 8-15, 1982 : mit Zusammenfassungen in Deutsch

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Physiology of the aerodigestive system and aberration in that system resulting in aspiration
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