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Toremifene

Toremifene is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene is FDA approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

Reference

Price N, Sartor O, Hutson T, Mariani S. Role of 5a-reductase inhibitors and selective estrogen receptor modulators as potential chemopreventive agents for prostate cancer. Clin Prostate Cancer 2005;3:211-4. PMID 15882476.

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		Gale Encyclopedia of Cancer : Toremifene $2.30			(99m)Tc-sestamibi imaging in the assessment of toremifene as a modulator of multidrug resistance in patients with breast cancer : An article from: The Journal of Nuclear Medicine $20.00

		Drug may prevent prostate Ca in high-risk patients: prostatic intraepithelial neoplasia patients who took toremifene had a 48% drop in prostate cancer ... : An article from: Family Practice News $5.95


	Toremifene Definition Toremifene, also known as Fareston, is a synthetic compound similar to estrogen. It mimics the action of estrogen on the bones and uterus, ... From Gale Encyclopedia of Cancer, by Sally C. McFarlane-Parrott

	Tamoxifen alone discouraged as adjuvant Tx HOLLYWOOD, FLA. -- An aromatase inhibitor, either alone or after tamoxifen therapy, is better than tamoxifen alone for the long-term prevention of breast ... From OB/GYN News, 5/1/05 by Diana Mahoney

	Big Question: Hormones, The What are the options? Recent findings about the drawbacks to estrogen (ET) and estrogen/progestin therapy (Combined Hormone Therapy - CHT) make it more ... From Friend Indeed, A, 3/1/05 by Cobb, Janine O'Leary

	Raloxifene: A Selective Estrogen Receptor Modulator Raloxifene is a selective estrogen receptor modulator that produces both estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic ... From American Family Physician, 9/15/99 by Janine A. Scott

	Drug shows promise on prostate cancer ORLANDO, Fla. -- A new study gives encouraging signs that a hormonal drug used to fight breast cancer might help prevent abnormal prostate growths from turning into cancers. Men who took low do From Deseret News (Salt Lake City), 5/15/05 by Marilynn Marchione Associated Press

	Drug that fights breast cancer also may prevent prostate tumors ORLANDO, Fla. -- A new study gives encouraging signs that a hormonal drug used to fight breast cancer might help prevent abnormal prostate growths from turning into cancers. Men who took low do From Chicago Sun-Times, 5/15/05 by MARILYNN MARCHIONE

	Coming soon to a pharmacy near you - designer estrogens - includes related article on how long a woman should take raloxifene After decades of selling American women and doctors on the idea that menopause is an illness that must be treated with lifelong estrogen therapy, the pharmaceutical industry is poised to unleash yet From Healthfacts, 1/1/98

	Medroxyprogesterone acetate Definition Medroxyprogesterone acetate (MPA) is used during cancer therapy to stop new cell growth in some cancers. It is also used outside of cancer treatment as a contraceptive. MPA is known From Gale Encyclopedia of Cancer, by A.M. Tish Davidson

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