Find information on thousands of medical conditions and prescription drugs.

Cervical cancer

Cervical cancer is a malignancy of the cervix. Worldwide, it is the second most common cancer of women. It may present with vaginal bleeding but symptoms may be absent until the cancer is in advanced stages, which has made cervical cancer the focus of intense screening efforts utilizing the Pap smear. Most scientific studies point to human papillomavirus (HPV) infection as a necessary pre-requisite for development of cervical cancer. Treatment is with surgery (including cryosurgery) in early stages and chemotherapy and radiotherapy in advanced stages of the disease. An effective vaccine for the two most common strains of HPV has recently been licenced (see below). more...

Home
Diseases
A
B
C
Angioedema
C syndrome
Cacophobia
Café au lait spot
Calcinosis cutis
Calculi
Campylobacter
Canavan leukodystrophy
Cancer
Candidiasis
Canga's bead symptom
Canine distemper
Carcinoid syndrome
Carcinoma, squamous cell
Carcinophobia
Cardiac arrest
Cardiofaciocutaneous...
Cardiomyopathy
Cardiophobia
Cardiospasm
Carnitine transporter...
Carnitine-acylcarnitine...
Caroli disease
Carotenemia
Carpal tunnel syndrome
Carpenter syndrome
Cartilage-hair hypoplasia
Castleman's disease
Cat-scratch disease
CATCH 22 syndrome
Causalgia
Cayler syndrome
CCHS
CDG syndrome
CDG syndrome type 1A
Celiac sprue
Cenani Lenz syndactylism
Ceramidase deficiency
Cerebellar ataxia
Cerebellar hypoplasia
Cerebral amyloid angiopathy
Cerebral aneurysm
Cerebral cavernous...
Cerebral gigantism
Cerebral palsy
Cerebral thrombosis
Ceroid lipofuscinois,...
Cervical cancer
Chagas disease
Chalazion
Chancroid
Charcot disease
Charcot-Marie-Tooth disease
CHARGE Association
Chediak-Higashi syndrome
Chemodectoma
Cherubism
Chickenpox
Chikungunya
Childhood disintegrative...
Chionophobia
Chlamydia
Chlamydia trachomatis
Cholangiocarcinoma
Cholecystitis
Cholelithiasis
Cholera
Cholestasis
Cholesterol pneumonia
Chondrocalcinosis
Chondrodystrophy
Chondromalacia
Chondrosarcoma
Chorea (disease)
Chorea acanthocytosis
Choriocarcinoma
Chorioretinitis
Choroid plexus cyst
Christmas disease
Chromhidrosis
Chromophobia
Chromosome 15q, partial...
Chromosome 15q, trisomy
Chromosome 22,...
Chronic fatigue immune...
Chronic fatigue syndrome
Chronic granulomatous...
Chronic lymphocytic leukemia
Chronic myelogenous leukemia
Chronic obstructive...
Chronic renal failure
Churg-Strauss syndrome
Ciguatera fish poisoning
Cinchonism
Citrullinemia
Cleft lip
Cleft palate
Climacophobia
Clinophobia
Cloacal exstrophy
Clubfoot
Cluster headache
Coccidioidomycosis
Cockayne's syndrome
Coffin-Lowry syndrome
Colitis
Color blindness
Colorado tick fever
Combined hyperlipidemia,...
Common cold
Common variable...
Compartment syndrome
Conductive hearing loss
Condyloma
Condyloma acuminatum
Cone dystrophy
Congenital adrenal...
Congenital afibrinogenemia
Congenital diaphragmatic...
Congenital erythropoietic...
Congenital facial diplegia
Congenital hypothyroidism
Congenital ichthyosis
Congenital syphilis
Congenital toxoplasmosis
Congestive heart disease
Conjunctivitis
Conn's syndrome
Constitutional growth delay
Conversion disorder
Coprophobia
Coproporhyria
Cor pulmonale
Cor triatriatum
Cornelia de Lange syndrome
Coronary heart disease
Cortical dysplasia
Corticobasal degeneration
Costello syndrome
Costochondritis
Cowpox
Craniodiaphyseal dysplasia
Craniofacial dysostosis
Craniostenosis
Craniosynostosis
CREST syndrome
Cretinism
Creutzfeldt-Jakob disease
Cri du chat
Cri du chat
Crohn's disease
Croup
Crouzon syndrome
Crouzonodermoskeletal...
Crow-Fukase syndrome
Cryoglobulinemia
Cryophobia
Cryptococcosis
Crystallophobia
Cushing's syndrome
Cutaneous larva migrans
Cutis verticis gyrata
Cyclic neutropenia
Cyclic vomiting syndrome
Cystic fibrosis
Cystinosis
Cystinuria
Cytomegalovirus
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
Restrictive cardiomyopathy
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Medicines

Signs and symptoms

The early stages of cervical cancer may be completely asymptomatic (Canavan & Doshi, 2000). Vaginal bleeding, contact bleeding or (rarely) a vaginal mass may indicate the presence of malignancy. In advanced disease, metastases may be present in the abdomen, lungs or elsewhere.

The possibility to identify premalignant changes on a cervical smear has made screening the major cause for referral of women with possible cervical neoplasia. In many countries, women are advised to have a regular Pap smear to check for premalignant changes. Recommendations for how often a Pap smear should be done vary from once a year to once every five years. If cervical cancer is detected early, it can be treated without impairing fertility. Consistently abnormal smears may be a reason for further diagnosis despite complete absence of symptoms.

Diagnosis

Diagnosis is made by doing a biopsy of the cervix, which often involves colposcopy, or a magnified visual inspection of the cervix aided by using an acetic acid solution to produce color changes in precancerous or cancerous areas. A Pap smear is insufficient for the diagnosis. Many researchers recommend that since more than 99% of invasive cervical cancers worldwide contain human papillomavirus, HPV testing should be carried out together with routine cervical screening (Walboomers et al, 1999). However, given the prevalence of HPV (around 80% infection history among the sexually active population) others suggest that routine HPV testing would cause undue alarm to carriers.

Further diagnostic procedures are loop electrical excision procedure (LEEP) and conisation, in which the inner lining of the cervix is removed to be examined pathologically. These are carried out if the biopsy confirms severe dysplasia.

Histology

Types of malignant cervical tumors include the following:

  • M8070/3: squamous cell carcinoma (about 80-85%)
  • M8140/3: adenocarcinoma
  • M8560/3: adenosquamous carcinomas
  • M8041/3: small cell carcinoma
  • M8246/3: neuroendocrine carcinoma
  • M8720/3: melanoma
  • (varied): lymphoma

Staging

Cervical cancer is staged by the FIGO staging system, which is based on clinical examination, rather than surgical findings. It allows only the following diagnostic tests to be used in determining the stage: palpation, inspection, colposcopy, endocervical curettage, hysteroscopy, cystoscopy, proctoscopy, intravenous urography, and X-ray examination of the lungs and skeleton, and cervical conization.

The TNM staging system for cervical cancer is analogous to the FIGO stage.

  • Stage 0 - full-thickness involvement of the epithelium without invasion into the stroma (carcinoma in situ)
  • Stage I - limited to the uterus
    • IA - diagnosed only by microscopy; no visible lesions
      • IA1 - stromal invasion less than 3 mm in depth and 7 mm or less in horizontal spread
      • IA2 - stromal invasion between 3 and 5 mm with horizontal spread of 7 mm or less
    • IB - visible lesion or a microscopic lesion with more than 5 mm of depth or horizontal spread of more than 7 mm
      • IB1 - visible lesion 4 cm or less in greatest dimension
      • IB2 - visible lesion more than 4 cm
  • Stage II - invades beyond uterus
    • IIA - without parametrial invasion
    • IIB - with parametrial invasion
  • Stage III - extends to pelvic wall or lower 1/3 of the vagina
    • IIIA - involves lower 1/3 of vagina
    • IIIB - extends to pelvic wall and/or causes hydronephrosis or non-functioning kidney
  • IVA - invades mucosa of bladder or rectum and/or extends beyond true pelvis
  • IVB - distant metastasis

Note that the FIGO stage does not incorporate lymph node involvement in contrast to the TNM staging for most other cancers.

Read more at Wikipedia.org


[List your site here Free!]


Warm needle therapy for the treatment of post cervical cancer radical surgery bladder numbness
From Townsend Letter for Doctors and Patients, 6/1/04 by Honora Lee Wolfe

Keywords: Chinese medicine, acupuncture, warm needle, post cervical cancer radical surgery bladder numbness

Radical hysterectomy for cervical cancer patients can damage the nerves associated with the bladder. Therefore, post-operative bladder numbness and urinary retention is not uncommon in these women. Xie Ying published an article titled, "A Clinical Audit of the Treatment of 136 Cases of Post Cervical Cancer Radical Surgery Bladder Numbness with Warm Needle Moxibustion," in issue #4, 2002 of Zhong Yi Za Zhi (Journal of Chinese Medicine) on page 267. A precis of this article appears below.

[ILLUSTRATION OMITTED]

Cohort description: One hundred thirty-six women with post-operative cervical cancer bladder numbness were divided into three groups. The treatment group was comprised of 49 women aged 24-69 years with an average age of 31.51 years. Twenty-five of the women had stage Ia cervical cancer, 16 had IIa, and eight had IIb stage cervical cancer. The acupuncture comparison group was comprised of 46 women, 25-66 years of age, with an average age of 34.46 years. Twenty-six of these women had stage Ia cervical cancer, 14 had Ib, and six had IIb. The other 41 women were assigned to the corpus vesicae procedure comparison group. This group was 23-68 years of age, with an average age of 32 years. Twenty-five of these women had stage Ia cervical cancer, 10 had IIa, and six had Iib. Therefore, there was no significant statistical differences between these three groups in terms of age or stage of disease.

Treatment method: The members of the treatment group were first needled at Guan Yuan (CV 4), Zhong Ji (CV 3), and Qi Hai (CV 6) with heads of the needles pointing to the perineum and then manipulated until a numb, distended feeling was propagated to that area. Then Zu San Li (St 36), San Yin Jiao (Sp 6), and Yin Ling Quan (Sp 9) were needled with supplementing hand technique. All these needles were retained for 30 minutes. During this time, two 2cm sections of moxa rolls were burned on each of the handles of these needles. This treatment was done once per day.

[ILLUSTRATION OMITTED]

The members of the acupuncture comparison group were needled at the same points but no moxibustion was burned. The needles were retained for 30 minutes each time, once per day.

The members of the corpus vesica procedure comparison group were urged to empty their bladders. Then an intravenous drip of 300-500ml of saline solution was administered. When the patient felt like her bladder was full, it was emptied by a catheter and another 500ml of saline solution was administered by intravenous drip. Again she emptied her bladder by catheter. This was done two times per day.

All three groups were treated for one week after which treatment outcomes were tabulated.

Treatment outcomes: Cure was defined as the ability to void the bladder by onself with less than 50ml residual urine. Improvement was defined as ability to void the urine on one's own but residual urine equal to or more than 50ml. No effect meant that one was still not able to empty one's bladder by herself and/or there was residual urine equal to or more than 100ml. Based on these criteria, 36 women in the treatment group were judged cured, 10 were improved, and three got no effect, for a total amelioration rate of 93.88%. In the acupuncture comparison group, 20 women were cured, 17 improved, and nine got no effect, for a total amelioration rate of 80.43%. In the corpus vesicae procedure comparison group, 13 women were cured, 12 improved, and 16 got no effect, for a total amelioration rate of only 60.98%. In the treatment group, the smallest number of treatment before seeing an effect was one and the greatest was seven, with an average of three treatments. Hence the warm needle treatment was markedly more effective than either acupuncture alone or the corpus vesicae procedure.

Translator's comments: While this article does not discuss a treatment specifically for cancer, in many states acupuncturists are not, strictly speaking, legally allowed to treat cancer. Acupuncturists in every state can, however, treat nausea, falling hair, fatigue, bladder numbness, or other common side effects of standard Western medical cancer treatments. Therefore, I chose this article to illustrate the efficacy of using acumoxa therapy to treat such side effects.

abstracted & translated by Honora Lee Wolfe, Dipl. Ac., Lic. Ac., FNAAOM c/o Blue Poppy Press * 5441 Western Ave. #2 * Boulder, Colorado 80301 USA www.bluepoppy.com

COPYRIGHT 2004 The Townsend Letter Group
COPYRIGHT 2004 Gale Group

Return to Cervical cancer
Home Contact Resources Exchange Links ebay