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Diphenoxylate

Diphenoxylate is an opioid agonist used for the treatment of diarrhea that acts by slowing down intestinal contractions. It is a congener to the narcotic Meperidine of which the common brand name is Demerol. This being the case, this medication is potentially habit-forming, particularly in high doses or when long time usage is involved. Because of this, diphenoxylate is manufactured and marketed as a combination drug with atropine (Lomotil®). more...

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This pharmaceutical strategy is designed to discourage abuse, because the anticholinergic effect of atropine will produce severe weakness and nausea if standard dosage is exceeded.

This medication is classifed as a Schedule V under the Controlled Substances Act by the FDA and the DEA in the United States.

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