The structure of Diethylcarbamazine

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Diethylcarbamazine

Diethylcarbamazine (DEC) (C₁₀H₂₁N₃O) is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. DEC is indicated for treatment of individual patients with certain filarial diseases. These diseases include: lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori; tropical pulmonary eosinophilia; and loiasis. more...

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Dextromethorphan

Dextropropoxyphene

Diethylcarbamazine

Diethylstilbestrol

Diethyltoluamide

Dihydroergotamine

Dihydrotachysterol

Dimethyl sulfoxide

Dimethyltryptamine

Diphenhydramine

Docusate sodium

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DEC continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.

Trade names

Carbilazine
Caricide
Cypip
Ethodryl
Notézine
Spatonin

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		Gale Encyclopedia of Medicine : Elephantiasis $5.99			Preventative chemotherapy of canine dirofilariasis with diethylcarbamazine (SAM-TR-68-95)

		Nature and control of side-reactions due to diethylcarbamazine in the treatment of Malayan filariasis


	Role Of Diethylcarbamazine In Patients Of Bronchial Asthma - A Clinical Study - DEC - Abstract Purpose: Leucotrienes have a role in pathogenesis of Bronchial asthma (BA). Modulation of production or action of leucotrienes can have therapeutic implication. DEC is known to inhibit formation of From CHEST, 10/1/99 by Jai Kishan

	Cost of mass annual single dose diethylcarbamazine distribution for the large scale control of lymphatic filariasis Economic analysis of the revised strategy to control lymphatic filariasis with mass annual single dose diethylcarbamazine (DEC) at 6 mg/kg body weight ... From Indian Journal of Medical Research, 3/1/00 by Krishnamoorthy, K

	Long-term effect of diethylcarbamazine citrate of microfilareamia status in treated individuals Follow up of microfilaraemic individuals infected with Wuchereria bancrofit at five years after treatment was carried out in a tea workers population. From Indian Journal of Medical Research, 10/1/98 by Khan, A M

	Endosymbiotic Wolbachia of parasitic filarial nematodes as drug targets The parasitic nematodes Wuchereria bancrofti, Brugia malayi and B. timori cause a dreadful disease in humans known as lymphatic filariasis, which afflicts ... From Indian Journal of Medical Research, 9/1/05 by Rao, Ramakrishna U

	Making the best of what we have: a plea for wider use of anthelmintics Over the last 15 yr, the World Health Assembly has passed several resolutions calling for the control, elimination or even eradication of diseases caused ... From Indian Journal of Medical Research, 7/1/05 by de Silva, Nilanthi

	Attack on elephantiasis. Antibiotic offers weapon against tropical scourge Of all the exotic diseases that afflict people, elephantiasis ranks among the most dreaded. The threadlike, parasitic worm that causes this lethal disease ... From Science News, 6/25/05 by N. Seppa

	A survey of bancroftian filariasis for microfilariae & circulating antigenaemia in two villages of Madhya Pradesh Background & objectives: The estimation of filariasis prevalence in Panna district of Madhya Pradesh was so far relied upon clinical and night blood smear ... From Indian Journal of Medical Research, 6/1/05 by Das, D

	Histopathologic improvement with lymphedema management, Leogane, Haiti In countries where bancroftian filariasis is endemic, lymphedema of the leg is a public health problem, particularly for women, who are disproportionately ... From Emerging Infectious Diseases, 11/1/04 by Susan F. Wilson

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