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Doxazosin

Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand name Cardura, is an alpha blocker used to treat high blood pressure and benign prostatic hyperplasia. It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.

Its empirical formula is C₂₃H₂₅N₅O₅•CH₄O₃S, and it has a molecular weight of 547.6.

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Ivax receives tentative approval for doxazosin mesylate tablets - Brief Article - Statistical Data Included
From Drug Store News, 8/28/00

The FDA has given tentative approval for Ivax Corp.'s ANDA for doxazosin mesylate in 1 mg., 2 mg., 4 mg. and 8 mg. tablet strengths.

Indicated for benign prostatic hyperplasia and hypertension, doxazosin mesylate tablets are the generic equivalent of Pfizer's Cardura, which had sales of approximately $313 million in the United States in 1999.

Miami-based IVAX will market the product through its wholly-owned subsidiary, Zenith Goldilne Pharmaceuticals.

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