Hoechst Marion Roussel's Amaryl (glimepiride tablets), a first-line treatment for type 2 diabetes, has received FDA approval for second-line combination use with metformin. Amaryl is the first and only drug in the sulfonylurea class to receive three indications; it has already been approved for use an as adjunct to diet and exercise as a monotherapy or in combination with insulin or in combination with insulin during second-line therapy.
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