Molecular structure of Naproxen
Find information on thousands of medical conditions and prescription drugs.

Anaprox

Naproxen (trade names: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the treatment of primary dysmenorrhea. It works by reducing hormones that cause inflammation and pain in the body. more...

Home
Diseases
Medicines
A
8-Hour Bayer
Abacavir
Abamectin
Abarelix
Abciximab
Abelcet
Abilify
Abreva
Acamprosate
Acarbose
Accolate
Accoleit
Accupril
Accurbron
Accure
Accuretic
Accutane
Acebutolol
Aceclidine
Acepromazine
Acesulfame
Acetaminophen
Acetazolamide
Acetohexamide
Acetohexamide
Acetylcholine chloride
Acetylcysteine
Acetyldigitoxin
Aciclovir
Acihexal
Acilac
Aciphex
Acitretin
Actifed
Actigall
Actiq
Actisite
Actonel
Actos
Acular
Acyclovir
Adalat
Adapalene
Adderall
Adefovir
Adrafinil
Adriamycin
Adriamycin
Advicor
Advil
Aerobid
Aerolate
Afrinol
Aggrenox
Agomelatine
Agrylin
Airomir
Alanine
Alavert
Albendazole
Alcaine
Alclometasone
Aldomet
Aldosterone
Alesse
Aleve
Alfenta
Alfentanil
Alfuzosin
Alimta
Alkeran
Alkeran
Allegra
Allopurinol
Alora
Alosetron
Alpidem
Alprazolam
Altace
Alteplase
Alvircept sudotox
Amantadine
Amaryl
Ambien
Ambisome
Amfetamine
Amicar
Amifostine
Amikacin
Amiloride
Amineptine
Aminocaproic acid
Aminoglutethimide
Aminophenazone
Aminophylline
Amiodarone
Amisulpride
Amitraz
Amitriptyline
Amlodipine
Amobarbital
Amohexal
Amoxapine
Amoxicillin
Amoxil
Amphetamine
Amphotec
Amphotericin B
Ampicillin
Anafranil
Anagrelide
Anakinra
Anaprox
Anastrozole
Ancef
Android
Anexsia
Aniracetam
Antabuse
Antitussive
Antivert
Apidra
Apresoline
Aquaphyllin
Aquaphyllin
Aranesp
Aranesp
Arava
Arestin
Arestin
Argatroban
Argatroban
Argatroban
Argatroban
Arginine
Arginine
Aricept
Aricept
Arimidex
Arimidex
Aripiprazole
Aripiprazole
Arixtra
Arixtra
Artane
Artane
Artemether
Artemether
Artemisinin
Artemisinin
Artesunate
Artesunate
Arthrotec
Arthrotec
Asacol
Ascorbic acid
Asmalix
Aspartame
Aspartic acid
Aspirin
Astemizole
Atacand
Atarax
Atehexal
Atenolol
Ativan
Atorvastatin
Atosiban
Atovaquone
Atridox
Atropine
Atrovent
Augmentin
Aureomycin
Avandia
Avapro
Avinza
Avizafone
Avobenzone
Avodart
Axid
Axotal
Azacitidine
Azahexal
Azathioprine
Azelaic acid
Azimilide
Azithromycin
Azlocillin
Azmacort
Aztreonam
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z

Although naproxen typically requires a higher dosage than other NSAIDs — a minimal dose is about 200 mg — it binds very well to albumin and thus achieves a longer half-life in the blood than other drugs, lasting up to 12 hours per dose.

Naproxen is also available as a sodium salt, naproxen sodium, which is more rapidly absorbed from the gastrointestinal tract.

Naproxen was first sold as the prescription drug Naprosyn in 1976; naproxen sodium was first sold under the trade name Anaprox in 1980. The Food and Drug Administration (FDA) approved naproxen sodium's use as an over-the-counter drug in 1991 , and it is sold in the United States as Aleve. Naproxen is still a prescription drug in much of the world, including Canada.

Structure and details

Naproxen is a member of the arylacetic acid family of NSAIDs. It is an odorless, white to off-white crystalline substance with a molecular weight of 230.2628. It is lipid-soluble, practically insoluble in water with a low pH (below pH 4), while freely soluble in water at 6 pH and above. Naproxen has a melting point of 153 °C.

Side effects and warnings

Like other NSAIDs, naproxen is capable of producing disturbances in the gastrointestinal tract. Taking the medication with food may help to alleviate this most commonly reported side-effect.

Also like other NSAIDs, naproxen can inhibit the excretion of sodium and lithium. Extreme care must be taken by those who use this drug along with lithium supplements.

Naproxen is also not recommended for use with NSAIDs of the salicylate family (drugs may reduce each other's effects), nor with anticoagulants (may increase risk of bleeding).

In December 2004, the FDA issued a press release following the decision by the National Institutes of Health to halt a five-year study, called the Alzheimer's Disease Anti-Inflammatory Prevention Trial. That study aimed to test both Aleve and Celebrex as preventatives for Alzheimer's disease. Preliminary information from the study showed naproxen elevated the risk of heart attack and stroke by 50%. The FDA advised patients taking over-the-counter naproxen products to:

  • carefully follow the instructions on the label,
  • avoid exceeding the recommended doses for naproxen (220 milligrams twice daily), and
  • take naproxen for no longer than ten days unless a physician directs otherwise.

Read more at Wikipedia.org


[List your site here Free!]


The Pharmacist and Homeopathy
From Townsend Letter for Doctors and Patients, 2/1/01 by Allen M. Kratz

Herb Rothouse, RPh considers himself a conventional pharmacist with an interest in complementary approaches to health care. I had the opportunity to talk with him about homeopathy in his pharmacy practice.

Allen Kratz, PharmD (AK): I understand your background as a pharmacist is unusual.

Herb Rothouse, RPh (HR): This is true, because my varied education pulls me in different directions. First of all, I am a conventional, by-the-book pharmacist you are used to seeing fill your prescriptions. But I also have a Master's Degree in Nutrition and I am a Licensed Nutritionist as well. I have been told there are fewer than twenty persons in the country with this dual licensure. This has given me a unique opportunity to offer guidance on diet and nutritional supplements along with drug information. This is a combination that very few pharmacists have.

But what has really made my career different has been learning and practicing homeopathy Many years ago when my European customers were asking for products I had never heard of and spoke of them in such glowing terms, I knew I had to learn as much as I could about them. So I did.

For the past 15 years, I have used, recommended, sold, written and lectured about homeopathic medicines with considerable and unexpected success. I cannot speak too highly of their safety and efficacy.

AK: In your published articles, you are very critical of the very prescriptions you dispense every day.

HR: Yes, and with good cause. For example, if we just look at the class of drugs called NSAIDs (Non-Steroid Anti-Inflammatory Drugs), we can see the problem. These drugs; Motrin [TM], Advil [TM], Aleve [TM], Indocin [TM], Clinoril [TM], Anaprox [TM], etc., kill between 15,000 and 17,000 persons each year. And if we combine the results of studies in JAMA, NEJM, The National Academy of Science Institute of Medicine, we find almost 250,000 Americans die each year from some physician-prescribed medication. Think about that. Almost 1 out of every 10 deaths in this country is physician-induced. This is more than serious... this is alarming.

AK: Since you see the dangers in these medications, how is it you still work as a pharmacist. Is this not hypocritical?

HR: No, because many medicines are essential to maintain good health. We must be more selective and choose the safer ones. The patient has to learn as much as possible about their condition and see what he/she can do on his/her own. Because of my education, Tam in a better position to advise and inform. Sometimes the answer is simply behavioral: no smoking, no alcohol, reduce caloric intake or exercise. Sometimes a nutritionist is needed for more intensive dietary alterations, and sometimes an acupuncturist or chiropractor or homeopath is necessary.

The first thing a patient has to consider is: how safe is this therapy? Then, what are the associated dangers and what are my alternatives?

AK: What are the safest healing modalities you have found?

HR: First of all, one modality will not solve all our health concerns. But clearly, there are advantages in each one. For example, acupuncture and acupressure are very safe. In fact, whenever I get a headache I put pressure on the Large intestine 4 spot. And for a sore throat, my first choice is Lung 11. For more serious conditions I turn to homeopathy. But homeopathy is not a one-size-fits-all therapy. You must be well trained to pick the correct medicine, and this can take considerable time to learn, even years. It is an art. This should not discourage anyone from starting to learn. There are many excellent books for a beginner where you can learn homeopathic first aid very quickly. I suggest you call Homeopathic Educational Services for a catalog, 510-649-0294.

AK: If homeopathic medicines are so effective, why don't more pharmacists suggest them?

HR: Two reasons. one...homeopathy is not a subject taught in pharmacy school, and two...most chain pharmacies do not promote or display them. To find homeopathic medicines, you have to go to a reputable health food store or locate a natural pharmacy, which is usually an independent pharmacy. If you need to locate a homeopathic practitioner, I suggest you contact the National Center for Homeopathy in Alexandria, Virginia, 703-548-7790.

AK: Aside from your pharmacy customers, how do you get your message out?

HR: As I have said, whenever opportunity and time allows and need warrants, I advise my customers not only on their prescription medication but the concerns and dangers attached to them and of the safer alternatives to investigate.

But to reach a larger audience, I write and lecture. I give a Continuing Education program called "Health, Healing and Homeopathy" to groups and organizations of health professionals, which has been very successful. It brings a great deal of new information to pharmacists and others about options they never knew existed. And that is the most important thing I can teach: there are safe alternatives to unsafe drugs.

AK: You said it can take years to learn homeopathy. What about all the OTC products that are available?

HR: For serious and chronic conditions you must be very cautious in selecting a homeopathic medicine and it is in that context that much study is required and an experienced homeopath is sometimes essential. But for the common, everyday disorders we get such as cold symptoms, or indigestion, or muscular aches and pains, the over-the-counter products are ideal. The homeopathic company has made it easier for you by selecting the medicines that relieve that particular discomfort. And since all homeopathic medicines are safe, there is no concern as we may find in many allopathic OTC products. In fact, the best product I ever sold and used for flu symptoms is Oscillococcinum[TM] made by Boiron.

AK: What is the most frequently asked question about homeopathy by pharmacists?

HR: "How do they work?" is probably the most common question I get from my fellow pharmacists. The answer is "we really don't know the exact mechanism of action." I then follow up by asking them "how many allopathic drugs do you dispense under the same circumstances?" This number is usually more than they realize. A quick read of the PDR may be enlightening.

AK: Are allopathic drugs used in a homeopathic manner?

HR: Yes, how about using a CNS stimulant in the hyperkinetic state of ADD? What about cancer chemotherapeutic drugs that can actually cause cancer? Even aspirin can cause headaches in toxic doses...all are homeopathic indications.

AK: There is much discussion today with the problem of food-drug interactions and drug-drug interactions. Do homeopathic products have these problems?

HR: In a word, no. There is absolutely no interaction between a homeopathic medicine with any allopathic medicine. However, for the homeopathic medicine to work best, it is used either 30 minutes before or after eating. You should have no concerns about safety or any adverse reactions.

AK: You mentioned Boiron. Are there any other companies that you recommend?

HR: I have confidence in homeopathic manufacturers that are FDA-registered, use NDC numbers for their products and are members of the American Association of Homeopathic Pharmacists. Companies like Boiron, Dolisos, HVS Labs, Standard Homeopathic and Boericke & Tafel come to mind.

AK: How can our readers reach you?

KR: My address is 10417 Canoe Brook Circle, Boca Raton, Florida 33498 USA, and my telephone is 561-482-0275.

COPYRIGHT 2001 The Townsend Letter Group
COPYRIGHT 2001 Gale Group

Return to Anaprox
Home Contact Resources Exchange Links ebay