Chemical structure of Aspartic acidChemical structure of the amino acid aspartate
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Aspartic acid

Aspartic acid (Asp), also known as aspartate, the name of its anion, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins. more...

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As with each of the 20 natural amino acids, there are two abbreviations commonly used to designate aspartic acid: Asp (three letter) and D (one letter). The abbreviations signifying a choice of either aspartic acid or asparagine are Asx (three-letter) and B (one letter).

As its name indicates, aspartic acid is the carboxylic acid analog of asparagine. It is non-essential in mammals, and might serve as an excitatory neurotransmitter in the brain. It is also a metabolite in the urea cycle, and participates in gluconeogenesis.

As a neurotransmitter, aspartic acid may provide resistance to fatigue and thus lead to endurance, although the evidence to support this idea is not strong.

Notes and references

  1. ^  IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. Nomenclature and Symbolism for Amino Acids and Peptides. Recommendations on Organic & Biochemical Nomenclature, Symbols & Terminology etc.. URL accessed on September 28, 2005.

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H+Blocker a new science in muscular performance: researchers agree, H+Blocker is quickly becoming the hottest bodybuilding supplement in America. But what
From Flex, 2/1/06

We all know how effective, and wildly popular, creatine has become. But has the next generation of bodybuilding supplementation finally arrived? New research from the United Kingdom, Russia, and Korea may be laying the foundation for a new performance aid called H+Blocker, which contains [beta]-alanine/L-histidine (a carnosine synthesizer), that is expected to eclipse the phenomenal success of creatine.

Skeptical? We don't blame you, especially considering the alarming number of bogus supplements on the market. That's why we tracked down the world's leading carnosine researcher--nutritional biochemist Mark Tallon, Ph.D.--to provide us with answers to our probing questions.

Q: What is H+Blocker[TM]?

A: H+Blocker is the world's first carnosine synthesizer/muscle intensifier ... used before intense exercise to block hydrogen, stabilize pH, and prevent "metabolic acidosis."

Q: What is carnosine?

A: In simple terms, carnosine is a di-peptide composed of [beta]-alanine and histidine, (1) which are the natural biological precursors for carnosine. (2)

Q: Where can I find carnosine?

A: I have helped formulate a new supplement, in collaboration with iSatori Technologies, based on my latest research, (3) which has recently been published in the Journal of Strength and Conditioning, with a specially bonded form of [beta]-alanine/L-histidine and aspartic acid, and it's being patented, so no one can copy it. It's called H+Blocker.

Q: How does H+Blocker work?

A: It is well known that increased muscle mass, strength, and extended performance occur most effectively when exercise routines are done to complete exhaustion. However, it is during intense workouts that we experience "metabolic acidosis"--a reaction in our bodies that causes muscle fatigue and failure. If we were to peek inside the muscle cells, we would see this reaction is brought on by the generation of hydrogen ions (H+) and a decline in muscle pH levels, and this is directly linked to a muscles' inability to contract any longer. (4)

The good news is I've found clear evidence that H+Blocker's patent-pending formula of [beta]-alanine/L-histidine increases the synthesis of carnosine, which binds to hydrogen ions and stabilizes pH levels in skeletal muscle. Imagine carnosine as a sponge that floats around the muscle, soaking up hydrogen ions, and the more carnosine inside the muscle, the more hydrogen ions it can soak up. As a result, with H+Blocker, one can experience immediate, almost explosive strength increases, more intense muscular contractions, as well as faster recovery between sets and workouts.

Q: What does the research say about carnosine and building muscle?

A: Interestingly to bodybuilders, research recently showed that carnosine has a direct and profound influence on Type II muscle fibers. (5) The reason this is so significant is because Type II fibers provide us with the fast-twitch muscle contractions that are "trainable" and are more easily influenced to undergo hypertrophy (muscle growth). (6) Better stated, Type II muscle fibers are what most of the top professional bodybuilders have more of, versus the Type I fibers. This, in theory, might be why it's easier for them to build more muscular bodies, faster and larger, than the rest of us.

Q: How can I use H+Blocker for optimal benefits?

A: A recent clinical study showed that 3.2 grams of [beta]-alanine/L-histidine taken daily prior to working out is sufficient to increase carnosine levels enough to impart significant benefits. (7) This is the exact amount contained in H+Blocker.

Q: What kind of results can I expect from using H+Blocker?

A: You will feel the muscle-stimulating effects of H+Blocker from the very first dose. You will immediately experience greater muscular contractions, fullness, and noticeably delay the onset of muscular fatigue ... thereby allowing you to train harder, longer, and require less recovery time between reps, sets, and workouts.

Here's more good news, evidence suggests that, unlike with other supplements (like creatine for instance), the benefits of H+Blocker will keep increasing the longer you take it. (8) Now that, in my humble opinion, is worth the investment alone.

There you have it ... with H+Blocker, don't expect miracle gains of 20 lbs overnight ... But do get ready for the absolute best, most intense, skin-splitting workouts of your life ... guaranteed. And, if you use it consistently for at least three to four weeks, work out hard, and eat plenty of protein, there's no reason you can't gain 5, 10, or 15 lbs of solid muscular bodyweight ... and add more strength to your max lifts than you could have ever imagined!

You can order H+Blocker at www.HBlocker.com or by calling 1-866-688-7679 (Dept. #2119). Or simply go to GNC and pick up your supply of H+Blocker today!

BE THE FIRST TO FEEL THE POWER OF H+BLOCKER AT

AN INTERVIEW WITH DR. MARK TALLON, PH.D.

RETAILER INQUIRIES WELCOME, CALL EUROPA AT 1-800-447-4795.

SCIENTIFIC REFERENCES:

(1) Bate-Smith, E.C., J Physiol 92 (1938): 336-43.

(2) Aonuma, S., et al., Yakugaku Zasshi 88.1 (1968): 1-7.

(3) Tallon, M.J., et al., J Strength Conditioning Sci 19.4 (2005): 725-9.

(4) Cooke, R., and Pate, E., Biophys J 48 (1985): 789-98.

(5) Harris, R.C., et al., J Sport Sci 16 (1998): 639-43.

(6) Suzuki, Y., et al., Jap J Physiol 52 (2002): 199-205.

(7) Harris, R.C., et al., Med Sci Sport Ex 35.5 (2003): abstract 1206.

(8) Hill, C.A., et al., American College of Sports Medicine Annual Meeting, Tennessee, 2005, Abstract #1833.

RELATED ARTICLE: QUICK FACTS

WHY YOU NEED H+BLOCKER

* Improves peak muscular contraction and muscle fullness [dagger]

* Intensifies workouts and maximizes total power output [dagger]

* Increases carnosine levels to allow higher maintenance of ATP [dagger]

* Influences Type II fast-twitch fibers [dagger] (seen more in muscular athletes and pro bodybuilders) [dagger]

* Enhances recovery time between reps, sets, and workouts [dagger]

COPYRIGHT 2006 Weider Publications
COPYRIGHT 2006 Gale Group

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