Ipratropium chemical structure
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Atrovent

Ipratropium is an anticholinergic drug (trade name: Atrovent®) administered by inhalation for the treatment of obstructive lung diseases. It acts by blocking muscarinic receptors in the lung, inhibiting bronchoconstriction and mucus secretion. more...

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Clinical uses

Ipratropium has respiratory effects similar to atropine but since it is poorly absorbed into the blood, it has few side effects (such as tachycardia) at therapeutic doses.

It is available under the trade names Alti-Ipratropium (AltiMed), Apo-Ipravent (Apotex), Atrovent Inhalation Aerosol (Boehringer Ingelheim), Atrovent Inhalation Solution (Boehringer Ingelheim), Atrovent Nasal Spray (Boehringer Ingelheim), Gen-Ipratropium (Genpharm), Novo-Ipramide (Novopharm), Nu-Ipratropium (Nu-Pharm), PMS-Ipratropuim (Pharmascience).

Sources

  • Brenner, G. M. (2000). Pharmacology. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
  • Canadian Pharmacists Association (2000). Compendium of Pharmaceuticals and Specialties (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4

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Atrovent Aerosol and Peanut Allergy - Statistical Data Included
From American Family Physician, 7/1/99 by Verna L. Rose

The Institute for Safe Medication Practices (ISMP) has issued an alert stating that the use of ipratropium aerosol (Atrovent inhalation aerosol) is contraindicated in patients with hypersensitivity to soya lecithin or related products, such as soybeans and peanuts. The alert, published in the October 21, 1998, issue of ISMP Medication Safety Alert, states that neither the package label nor the patient instruction sheet mentions a contraindication for patients with peanut allergy. The ISMP points out that patients with peanut allergy can use Atrovent nasal spray or inhalation solution because neither contains soya lecithin. The ISMP has recommended that the manufacturer strengthen warnings about peanut allergies in patient and professional information. For more information on safe medication practices, visit the ISMP Web site at http://www.ismp.org.

COPYRIGHT 1999 American Academy of Family Physicians
COPYRIGHT 2000 Gale Group

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