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Augmentin

Co-amoxiclav is the British Approved Name, in the British Pharmacopoeia, for the combination antibiotic containing Amoxicillin (as either trihydate or the sodium salt) and Clavulanic acid (as Potassium clavulanate). This name, unlike co-trimoxazole, has not been widely adopted internationally and the combination product is usually referred to by various names such as amoxicillin with clavulanic acid or amoxicillin+clavulanate or simply by the trade name. more...

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Co-amoxiclav is currently marketed by GlaxoSmithKline under the trade name Augmentin®, and by Pfizer as Clavamox® (Clavamox® is for veterinary use only).

The combination of amoxicillin, a β-lactam antibiotic; with clavulanic acid, a β-lactamase inhibitor; results in an antibiotic with an increased spectrum of action and restored efficacy against β-lactamase producing amoxicillin-resistant bacteria.

Dosage

  • Co-amoxiclav sensitive organisms

Side effects

Amongst the possible side-effects of this medication are diarrhoea, vomiting and a few other conditions. These do not usually require medical attention. However, if the patient experiences an allergic reaction to the medication, jaundice, fever or severe diarrhoea, it is necessary to contact a doctor immediately.

Amoxicillin is a member of the penicillin family of antibiotics, and therefore should not be taken by patients allergic to penicillin.

Read more at Wikipedia.org


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GlaxoSmithKline reported late last month that the FDA has approved an extended-release form of its antibiotic Augmentin, offering a partial defense against
From Drug Store News, 11/4/02

GlaxoSmithKline reported late last month that the FDA has approved an extended-release form of its antibiotic Augmentin, offering a partial defense against generic competition. Late last year, the FDA had asked for additional information before approving Augmentin XR. Augmentin was GSK's second-largest product in 2001 with worldwide sales of $2.2 billion, including $912 million in the United States. Geneva Pharmaceuticals, a unit of Novartis, has been selling generic Augmentin in the United States since July. GSK also is fighting a legal battle to win back exclusivity on Augmentin, arguing it has valid U.S. patents that should give it protection to 2017 or 2018. An appeal in the patent case is expected to be heard next year.

COPYRIGHT 2002 Reproduced with permission of the copyright holder. Further reproduction or distribution is prohibited without permission.
COPYRIGHT 2002 Gale Group

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