Irbesartan chemical structure
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Avapro

Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Irbesartan was discovered by Sanofi Research (now part of Sanofi-Aventis). It is jointly marketed by Sanofi-Aventis and Bristol-Myers Squibb under the trade names Aprovel®, Karvea®, and Avapro®. more...

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Irbesartan is one of the class that patients may be prescribed if they cannot tolerate the ACE-inhibitor drugs, such as perindopril. The usual reason is because of dry cough, attributed to delayed breakdown of bradykinin by ACE. Irbesartan may help to delay the progression of diabetic nephropathy, a form of chronic renal failure due to diabetes.

Irbesartan is also available in a combination formulation with hydrochlorothiazide, marketed as CoAprovel®.

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Are you making the healthiest choices?
From Shape, 10/1/04

Every day, you make choices about your health and well--being. But are you making the right ones? Take another look at some of the decisions you face each day, and see if your choices are the best ones for you and your body.

The Breakfast Club

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Work It Out

Can't find time to exercise? You've got choices. Opt for a morning workout--you'll fit in fitness and gain energy for the day. If you still can't swing it, make the choice to exercise whenever you can--take the stairs instead of the elevator, or get off the bus a few stops early and walk the rest of the way to work.

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Important safety information about Yasmin:

What makes Yasmin[R] different from other birth control pills?

It contains a different kind of progestin which may increase potassium. For healthy women this is not a problem.

How can you be sure Yasmin is safe for you?

Consult your doctor. You should not take Yasmin if you have kidney, liver or adrenal disease because this could cause serious heart and health problems.

What drugs could interfere with Yasmin?

Potassium-increasing drugs. Tell your doctor if you are on daily, long-term treatment for a chronic condition with any of the following: NSAIDs-ibuprofen (Motrin[R], Advil[R]), naproxen (Naprosyn[R], Aleve[R], and others) when taken long-term and daily for arthritis or other diseases or conditions, potassium-sparing diuretics (spironolactone and others), potassium supplementation, ACE inhibitors (Capoten[R], Vasotec[R], Zestril[R], and others). Angiotensin-II receptor antagonists (Cozaar[R], Diovan[R], Avapro[R], and others), and Heparin. Women who take any of the preceding drugs every day should have their potassium level checked in the first month of taking Yasmin.

What are the risks involved with taking any oral contraceptive (OC)?

OCs can be associated with increased risks of several serious side effects, and do not protect against HIV infection or other STDs. Women, particularly those 35 and over, are strongly advised not to smoke due to the risk of serious cardiovascular side effects.

COPYRIGHT 2004 Weider Publications
COPYRIGHT 2004 Gale Group

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