ANTIHYPERTENSIVE DRUGS
Patients taking angiotensin-converting enzyme (ACE) inhibitors such as lisinopril (Zestril) or angiotensin-receptor blockers such as irbesartan (Avapro) for hypertension and other cardiovascular conditions should be carefully monitored for potassium overload, according to researchers. About 10% of patients taking ACE inhibitors develop hyperkalemia within a year after the drugs are prescribed. Patients with kidney problems and diabetes are particularly at risk. Signs and symptoms of hyperkalemia include diminished deep tendon reflexes, weakness, palpitations, and arrhythmias.
Patients taking these drugs should avoid taking other drugs and products that impair potassium excretion, including the nonsteroidal antiinflammatory drugs ibuprofen and naproxen, and herbal remedies containing potassium. Teach patients to avoid foods that are high in potassium, such as orange juice, melons, bananas, and salt substitutes.
Source: "Managing Hyperkalemia Caused by Inhibitors of the Renin-Angiotensin-Aldoslerone System," The New England Journal of Medicine, B. Palmer, August 5, 2004.
Copyright Springhouse Corporation Nov 2004
Provided by ProQuest Information and Learning Company. All rights Reserved
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