Fexofenadine chemical structure
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Fexofenadine

Fexofenadine hydrochloride (brand names include Allegra® and Telfast®) is an antihistamine drug used in the treatment of hayfever and similar allergy symptoms. It was developed as a successor of and alternative to terfenadine, an antihistamine with potentially fatal contraindications. more...

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History

Fexofenadine was developed by Hoechst Marion Roussel (now part of Aventis) and approved by the FDA in 1996. Since that time, it has achieved blockbuster drug status with global sales of $1.87B USD in 2004 (with $1.49B USD coming from the United States).

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Mylan Laboratories
From Drug Store News, 6/21/04

The FDA granted Mylan Laboratories tentative approval for its abbreviated new drug application for fexofenadine hydrochloride and pseudoephedrine hydrochloride extended-release tablets in 60 mg and 120 mg doses. The tablets are the generic equivalent of Aventis Pharmaceuticals' Allegra-D extended-release tablets for the treatment of allergic rhinitis.

According to Aventis Pharmaceuticals, the number of U.S. cases of allergic rhinitis is expected to climb to more than 64 million by 2011.

COPYRIGHT 2004 Reproduced with permission of the copyright holder. Further reproduction or distribution is prohibited without permission.
COPYRIGHT 2004 Gale Group

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