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Fludrocortisone

Fludrocortisone acetate is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. It is used primarily to replace mineralocorticoids in various forms of adrenal insufficiency such as Addison's disease and congenital adrenal hypoplasia. It is occasionally used to treat orthostatic hypotension as well.

The brand name in the U.S. is Florinef. It is available in 0.1 mg tablets. Typical daily doses for mineralocorticoid replacement are 1/2 to 2 tablets a day. In this dose glucocorticoid effect is minimal.

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Fludrocortisone

Fluorometholone

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		One week of low-dose steroids led to 10% drop in deaths due to septic shock, renal failure. (Hydrocortisone and Fludrocortisone). : An article from: Internal Medicine News $5.95			"Fludrocortisone role in central regulation of fluid balance" : final report NASA-Ames NCC 2-764 : period covered, 7/1/93-1/15/96 (SuDoc NAS 1.26:206754)


	Fludrocortisone Not Effective in Chronic Fatigue Fludrocortisone therapy did not result in adequate improvement of neurally mediated hypotension in a study of 83 patients who had chronic fatigue syndrome, ... From Family Pratice News, 5/15/01 by Mary Ann Moon

	Hydrocortisone Infusion for Severe Community-acquired Pneumonia: The Role of Relative Adrenal Insufficiency/From the Authors To the Editor. The recent study by Dr. Confalonieri and colleagues (1), about the beneficial effect of low-dose hydrocortisone on the outcome of severe ... From American Journal of Respiratory and Critical Care Medicine, 9/15/05 by Jalloul, Ahmad

	Etomidate for endotracheal intubation in sepsis: acknowledging the good while accepting the bad We would like to commend Dr. Jackson (see page 1031) on both his historical review and critical appraisal of the use of etomidate as an anesthetic induction ... From CHEST, 3/1/05 by Holt Murray

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	Growth hormone, vasopressin and prolactin This month's column wraps up the section on hormonal dysfunctions in chronic fatigue syndrome and fibromyalgia. We have discussed the importance of treating an underactive thyroid and adrenal gland From Townsend Letter for Doctors and Patients, 8/1/04 by Jacob Teitelbaum

	Low-dose steroid replacement in severe sepsis—response In response to the Letter to the Editor by Doson Chua in the April issue (2004:16), I disagree with her statement that the use of steroid therapy is ... From Critical Care Nurse, 6/1/04 by Karen Aloe

	Low-dose steroid replacement in severe sepsis Letters to the Editor are welcome and encouraged. Letters must address topics that have previously appeared in Critical Care Nurse. Keep your letters ... From Critical Care Nurse, 4/1/04 by Doson Chua

	Diary from a week in practice Monday There is something cartoonish about Bernardo Marroquin--dangling arms, head that looks like it's rolling off his kyphotic neck, lumpish face ... From American Family Physician, 3/15/04 by Paul Gross

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