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Fusidic acid

Fusidic acid is an antibacterial antibiotic used particularly for eye and skin infections. It works by interfering with bacterial protein synthesis, specifically by preventing the translocation of the elongation factor G (EF-G) from the ribosome, although it works only on gram-positive bacteria such as Staphylococcus aureus, Streptococcus and Corynebacterium minutissimum. It was first isolated in 1962 from the fungus Fusidium coccineum, and later from Mucor ramannianus and Isaria kogana. more...

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It is delivered as an ointment, a cream or eye drops.

Brand names

  • Fusidin (of Leo in Canada)
  • Fucidin
  • Fucithalmic (of Leo in UK and Denmark)

Reference

  • RxMed Monograph
  • Synthesis of photoreactive fusidic acid analogues for binding studies with elongation factor G

Read more at Wikipedia.org


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Prospective comparative study of Fusidic acid, Vancomycin and Cefuroxime, in prophylactic use in T.H.R and T.K.R. early results
Aims: Evaluation of postoperative infections in T.H.R. and T.K.R., after randomized prophylactic use of Fusidic acid, Vancomycin and Cefuroxime and assessment ...
Treatment of uncomplicated skin and skin structure infections in the diabetic patient
Abstract Diabetic neuropathy can lead to the development of ulcers on the lower extremities. Prompt treatment lowers the likelihood of infection and ...
Methicillin-resistant Staphylococcus aureus necrotizing pneumonia
To the Editor: Methicillin-resistant Staphylococcus aureus (MRSA) strains account for >40% of all hospital-acquired S. aureus infections in Italy ...
Bacterial contaminants and antibiotic prophylaxis in total hip arthroplasty
We have investigated the contaminating bacteria in primary hip arthroplasty and their sensitivity to the prophylactic antibiotics currently in use. Impressions ...
Partial protective effect of rutin on multiple low dose streptozotocin-induced diabetes in mice
Byline: K. Srinivasan, C. Kaul, P. Ramarao Type 1 diabetes or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disorder affecting approximately ...
Differential growth of epidemic methicillin-resistant Staphylococcus aureus in vancomycin
ABSTRACT This study examines the ability of isolates representing the 17 epidemic methicillin-resistant strains of Staphylococcus aureus to grow in increasing ...
Community-associated methicillin-resistant Staphylococcus aureus, Canada
A total of 184 methicillin-resistant Staphylococcus aureus (MRSA) strains were collected from patients who sought treatment primarily for skin and soft ...
care of pin sites with external fixation, The
Two protocols for the operative technique and care of the pin-site with external fixation were compared prospectively. There was a total of 120 patients ...

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