Fluticasone chemical structure
Find information on thousands of medical conditions and prescription drugs.

Flonase

Fluticasone proprionate is a glucocorticoid often prescribed as treatment for asthma and allergic rhinitis. It is marketed with the brand name Flixotide® and Flixonase® by Allen & Hanburys and Flovent® and Flonase® by GlaxoSmithKline. more...

Home
Diseases
Medicines
A
B
C
D
E
F
Captagon
Famohexal
Famotidine
Faslodex
Faslodex
Fasoracetam
Felbamate
Felbatol
Felodipine
Felypressin
Femara
Femara
Fempatch
Femring
Fenfluramine
Fenofibrate
Fentanyl
Fexofenadine
Filgrastim
Filipin
Finasteride
Fioricet
Fiorinal
Flagyl
Flarex
Flavoxate
Flecainide
Flexeril
Flomax
Flonase
Flovent
Floxuridine
Fluacizine
Flucloxacillin
Fluconazole
Flucytosine
Fludarabine
Fludrocortisone
Flumazenil
Flunisolide
Flunitrazepam
Fluocinonide
Fluohexal
Fluorometholone
Fluorouracil
Fluoxetine
Fluphenazine
Flurazepam
Flutamide
Fluticasone
Fluvastatin
Fluvoxamine
FML
Focalin
Folic acid
Follutein
Fomepizole
Formoterol
Fortamet
Fortovase
Fosamax
Fosinopril
Fosinoprilat
Fosmidomycin
Fosphenytoin
Frova
Frovatriptan
Frusehexal
Fulvestrant
Fumagillin
Furazolidone
Furosemide
Furoxone
Fusafungine
Fusidic acid
Fuzeon
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z

How it works

The precise mechanisms of glucocorticoid action in asthma are unknown. Inflammation is recognized as an important component in the pathogenesis of asthma. Glucocorticoids have been shown to inhibit multiple cell types (e.g., mast cells, eosinophils, basophils, lymphocytes, macrophages, and neutrophils) and mediator production or secretion (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in the asthmatic response. These anti-inflammatory actions of glucocorticoids may contribute to their efficacy in asthma. Typically, however, the action on the cells affected requires several days. Therefore, inhaled steroids are not used for immediate relief of asthma, but instead as preventive and maintenance therapy.

Clinical trials

This listing is NOT complete and should NOT be construed as support for treatment decisions. See also PubMed clinical manuscripts referring to fluticasone

  • Burge, P.S.; Calverley, P.M.; Jones, P.W.; Spencer, S.; Anderson, J.A.; and Maslen T.K. (2000). Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial. British Medical Journal 320 (7245), 1297-1303. PMID 10807619.
  • Paggiaro, P.L.; Dahle, R.; Bakran, I.; Frith, L.; Hollingworth, K.; and Efthimiou, J. (1998). Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. The Lancet 351 (9105), 773-780. PMID 9519948.
both support a positive outcome for use of fluticasone in patients with chronic obstructive pulmonary disease, also referred to as COPD

Read more at Wikipedia.org


[List your site here Free!]


4 ways to cut health-care costs: this is the season for selecting a health-insurance plan. Here's how to choose wisely—and save hundreds
From Shape, 11/1/04 by Fran Kritz

Have you received that hefty packet detailing your health benefits from the human-resources department yet? If not, you'll likely get one soon, as fall is the time many companies ask their employees to rethink their insurance coverage. And while 80 percent of us will simply check off what we had last year, benefits experts say that can be an expensive mistake. As insurance costs for companies rise, you can bet some of that burden will shift to employees. But by choosing the smartest insurance plan and taking advantage of other ways your employer or insurer can pick up more of the tab, you can still save hundreds of dollars next year.

The catch? You need to invest some time and effort: Read that benefits packet carefully, and visit your insurance company's Web site or call their customer-service representative. Here, four of the best ways to shave costs.

1. DO THE MATH

Choosing the health-insurance plan that will ultimately cost you the least while providing the care you want is no simple task. Most people look at just one number when deciding between insurance options: the monthly contribution their employer charges for coverage, says Richard Ostuw, a consultant with benefits firm Towers Perrin in New York City. But also knowing what you're likely to spend out-of-pocket in the coming year is crucial.

First off, ask your insurance company's customer-service department for a tally of fees you paid yourself in 2004, then break them down into co-payments for doctor's visits, co-pays for prescription drugs, and the like. Remember to factor in what the co-pay would be for an emergency-room visit or hospital stay in case of injury, especially if you participate in active sports.

Two more numbers to pay attention to are your deductible, or the amount you have to pay before your benefits kick in, and your co-insurance, or the percentage of physician's fees you're responsible for. Many managed-care plans don't have a deductible and pay 100 percent of physician's fees, but you're restricted on which doctors you can see, so you need to consider how much you're willing to compromise in your choice of physicians.

Next, evaluate in tandem these four factors: your annual contribution; out-of-pocket costs; deductible; and coinsurance, for each insurance plan your company offers to determine the one under which you'll likely pay the least. Your company may offer online calculators or worksheets to help you compare your costs, or you can use ours as a basic guide (see page 117). The online federal guide "Choosing and Using a Health Plan" at www.ahrq.gov/consumer/hlthpln1.htm#choices is an excellent general resource.

2. OPEN A FLEXIBLE SPENDING ACCOUNT

Flexible spending accounts (FSAs), offered by many companies, let you deduct pre-tax money--usually up to $5,000 a year--from your paycheck to pay medical costs not covered by health insurance. These include everything from cough syrup to LASIK vision correction to certain types of cosmetic surgery and fertility treatments.

It's up to each company to decide which expenditures are eligible, but WageWorks, a San Mateo, Calif., benefits consulting firm, offers a list of commonly allowed FSA expenses at www.wageworksmarket.com/eligible, as well as a calculator that can help you decide how much to put aside in an FSA account at www.wageworksmarket.com/calc/.

The one rule most people know about FSAs is that you lose whatever money you haven't spent by the end of the year, which is one reason only about 15 percent of those eligible sign up for an FSA account. But benefits experts estimate that no more than $20 is generally left over--funds that easily could be used up at the end of the year on a few boxes of over-the-counter allergy drugs.

HOW IT WORKS You could shell out up to $750 a year on nonreimbursed vision-care costs for things like eye exams, glasses, prescription sunglasses, contacts and contact-lens solution. But pull that money out of your FSA instead and you'll save yourself an average of 30 percent, or about $225, depending on your tax bracket, because you're using pre-tax income.

3. GET YOUR GOOD HABITS SUBSIDIZED

Hoping to keep you healthy (and thus less of a liability for them), most insurers offer discounts on such "good health behaviors" as gym memberships, weight-loss groups--even massage. The "Healthy Rewards" program from national insurer Cigna, for example, provides savings of up to 60 percent on chiropractic care, acupuncture, supplements, health and fitness magazine subscriptions, and smoking-cessation programs. Check your insurer's Web site (look for a "wellness" section) to find out about other discounts, or phone the customer-service rep (the number is usually in your sign-up packet or on the back of your insurance card).

HOW IT WORKS Aetna, among other insurers, has contracted with fitness provider GlobalFit to offer discounts on gym memberships, supplements, gear and home gym equipment, including $200 off a treadmill. Aetna members can purchase the discounted items at globalfit.com.

4. SAVE ON DRUG COSTS

Even if you live a healthy lifestyle, you may still take some kind of prescription medication. Drug co-payments are one of the easiest areas to shift costs to workers, but there are some simple ways to save money.

* Always ask your physician if samples are available. Often the sample pack is a full course of the medicine you need. Doctors also may have coupons redeemable for samples at the pharmacy.

* Look online for coupons for popular drugs. At flonase.com, for example, you'll find a printable coupon for $5 off four prescriptions whether you pay cash or a co-pay for the allergy drug.

* Use mail-order pharmacies. A great option for drugs you take daily, such as asthma medication or birth-control pills; when you use a mail-order pharmacy it's standard to pay two co-pays and get a three-month supply.

* Ask your doctor about generic options. Like brand-name drugs, generics must be approved by the U.S. Food and Drug Administration and have an excellent safety record. The typical co-pay is $10 or less, compared with up to $25 for the brand-name version.

* Find out if the drug your doctor calls for is covered by your insurance before you fill the prescription. If it's not, ask your physician if another brand, or a generic, would work just as well, or you could be paying the entire cost of the medication yourself.

HOW IT WORKS If your company doesn't cover birth control, you'll pay $38 for a month's worth of Ortho Novum 7/7/7 at drugstore.com. Switch to the generic ($27) and you'll get an extra $132 in your pocket each year. Pay for it with pre-tax dollars from your FSA and your savings bump to $172 annually.

Now get going and start tackling that insurance packet!

RELATED ARTICLE: Crunching the numbers

Use this worksheet to compare costs among health-insurance plans offered by your employer for 2005. Have last year's information at hand; you can use the total cost of doctor visits, prescriptions, etc., to project likely expenses for next year.

RELATED ARTICLE: New in 2005: Health Savings Accounts

A small percentage of companies will offer Health Savings Accounts (HSAs) next year, with more expected to follow suit in 2006. Like flexible spending accounts (FSAs), these are tax-free accounts to pay for health-care costs not covered by insurance, such as doctor co-pays, vision and dental care, insurance deductibles and some nonprescription drugs. Unlike FSAs, however, the new accounts can be rolled over each year--something the government hopes you'll do so you'll have money saved up to spend on health care when you retire. For more info on HSAs, visit the Department of Treasury at www.treas.gov/offices/public-affairs/hsa/faq1.shtml.

Fran Kritz, a Silver Spring, Md.-based free-lance writer, has good health-insurance coverage (thanks to her husband's employer), but no flexible spending account.

COPYRIGHT 2004 Weider Publications
COPYRIGHT 2004 Gale Group

Return to Flonase
Home Contact Resources Exchange Links ebay