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Methocarbamol

Methocarbamol (chemical formula: ) is a central muscle relaxant for skeletal muscles, used to treat spasms. Robaxin and Robaxacet are trade names for methocarbamol. It is structurally related to guaifenesin. more...

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References and End Notes

  • Methocarbamol The Elephant Formulary
  • PubChem Substance Summary: Methocarbamol National Center for Biotechnology Information.
  • Alphabetical Listing of ATC drugs and codes (PDF) mSupply, by Sustainable Solutions. Katmandu, Nepal.
  1. ^  Sica DA, Comstock TJ, Davis J, Manning L, Powell R, Melikian A, Wright G. "Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals." European Journal of Clinical Pharmacology. 1990;39(2):193-4. PMID 2253675

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Drug challenge
From Nursing, 2/1/99

You routinely administer combination drugs...but do you know what's in them? To find out, match each combination of ingredients in Section II with its correct name in Section I.

SECTION I

1. Robaxisal (Robins)

2. Sinemet-25/100 (DuPont Pharm)

3. NeoDecadron Solution (Merck)

4. Ambenyl-D Liquid (Forest)

5. Axocet (Savage Labs)

SECTION II

a. methocarbamol, 400 mg; aspirin, 325 mg Patients with acute, painful muscle spasms may find relief with this prescription tablet. Methocarbamol is a muscle relaxant; aspirin, a salicylate, relieves inflammation and pain. Your patient may experience dizziness or drowsiness.

b. neomycin sulfate, 0.35%; dexamethasone phosphate, 0.1% These eyedrops may be prescribed to treat an eye infection accompanied by ocular inflammation. Neomycin sulfate is a topical antibiotic; dexamethasone phosphate is a corticosteroid.

c. butalbital, 50 mg; acetaminophen, 650 mg Patients suffering from tension headaches will benefit from this capsule. Butalbital, a short-acting barbiturate, provides sedation and relieves tension; acetaminophen is a nonopioid analgesic. Warn your patient that this combination may be habit-forming, so he shouldn't exceed the recommended dosage.

d. levodopa, 100 mg; carbidopa, 25 mg This combination may be prescribed to control the symptoms of Parkinson's disease, such as tremor, rigidity, and unsteadiness. Levodopa, which is metabolized to dopamine, replaces the dopamine deficiency in the brain that causes Parkinson's symptoms. Carbidopa isn't active against symptoms but enhances the effectiveness of levodopa by preventing levodopa metabolism outside the brain.

e. dextromethorphan, 15 mg; guaifenesin, 100 mg; pseudoephedrine HCI, 30 mg

A patient may select this nonprescription liquid as a treatment for cold symptoms. Dextromethorpan is a nonopioid cough supressant; guaifenesin, an expectorant, thins bronchial mucus. Pseudoephedrine HCl, a sympathomimetic, is a decongestant. Warn your patients to avoid products containing other sympathomimetics, such as phenylephrine and phenylpropanolamine.

Marcy Portnoff Gever, RPh, MEd, author of Drug Challenge, is drug information editor for Nursing99.

Copyright Springhouse Corporation Feb 1999
Provided by ProQuest Information and Learning Company. All rights Reserved

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