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Methoxsalen

Methoxsalen (marketed under the trade name oxsoralen) is a drug used to treat psoriasis in conjunction with exposing the skin to sunlight. Methoxsalen modifies the way skin cells receive the UVA radiation, allegedly clearing up the disease. The dosage comes in 10mg tablets, which are taken in the amount of 30mg 75 minutes before a PUVA light treatment. more...

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Patients with high blood pressure or a history of liver problems are at risk for inflammation and irreparable damage to both liver and skin. The eyes must be protected from UVA radiation. Side effects include nausea, headaches, dizziness, and in rare cases insomnia.

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	NTP technical report on the toxicology and carcinogenesis studies of 8-methoxypsoralen (CAS no. 298-81-7) in F344/N rats (gavage studies) (SuDoc HE 20.3159/2:359)


An intraindividual study of the characteristics of erythema induced by bath and oral methoxsalen photochemotherapy and narrowband ultraviolet B[para] Received 13 December 2002; accepted 16 April 2003 ABSTRACT We compared the characteristics of psoralen and ultraviolet A (PUVA) erythema in skin photosensitized ... From Photochemistry and Photobiology, 7/1/03 by Man, Irene

Pipeline previews New Drug Application 9-048/S-037 Approval Date: 3/26/03 Name: 8-MOP (methoxsalen) Capsules Applicant: ICN Pharmaceuticals OTC/RX status: RX From Journal of Drugs in Dermatology, 8/1/03

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High mutation frequency at Ha-ras exons 1-4 in squamous cell carcinomas from PUVA-treated psoriasis patients High Mutation Frequency at Ha-ras Exons 1-4 in Squamous Cell Carcinomas from PUVA-treated Psoriasis Patients ABSTRACT Clinical follow-up studies have ... From Photochemistry and Photobiology, 8/1/01 by Kreimer-Erlacher, Heidemarie

Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells Oral Aminolevulinic Acid Induces Protoporphyrin IX Fluorescence in Psoriatic Plaques and Peripheral Blood Cells^(par) ABSTRACT Photodynamic therapy (PDT) with topical aminolevulinic acid (ALA) has From Photochemistry and Photobiology, 8/1/01 by Bissonnette, Robert

Carcinogens Substances capable of causing cancer. From Gale Encyclopedia of Childhood and Adolescence, 4/6/01

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