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Methohexital

Methohexital is a short-acting intravenous anaesthetic induction agent, that is, used to commence anaesthesia.

Rapid onset and short duration of action, similar to thiopentone, with which it competed.

The drug was provided in multi-dose bottles, which have fallen from favour these days.

It was a reliable agent, favoured by some anaesthesiologists to thiopentone, although thought by many to be not so smooth as thiopentone.

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Propofol Administration
From Georgia Nursing, 5/1/05

The Georgia Board of Nursing recognizes that the administration of Propofol is a very serious and complicated medication and supports the following statement by the American Association of Nurse Anesthetists and the American Society of Anesthesiologists:

AANA-ASA Joint Statement Regarding Propofol Administration*

Because sedation is a continuum, it is not always possible to predict how an individual patient will respond. Due to the potential for rapid, profound changes in sedative/anesthetic department and the lack of antagonistic medications, agents such as propofol require special attention.

Whenever propofol is used for sedation/ anesthesia, it should be administered only by persons trained in the administration of general anesthesia, who are not simultaneously involved in these surgical or diagnostic procedures. This restriction is concordant with specific language in the propofol package insert, and failure to follow these recommendations could put patients at increased risk of significant injury or death. Similar concerns apply when other intravenous induction agents are used for sedation, such as thiopental, methohexital or etomidate.

* This statement is not intended to apply when propofol is given to intubated, ventilated patients in a critical care setting.

ASA (American Society of Anesthesiologists) AANA (American Association of Nurse Anesthetists)

Copyright Georgia Nurses Association May-Jul 2005
Provided by ProQuest Information and Learning Company. All rights Reserved

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