Find information on thousands of medical conditions and prescription drugs.

Motrin

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen; a standing joke about some athletes' regular use has produced "Vitamin I" as a slang term for it. It is used for relief of symptoms of arthritis, primary dysmenorrhoea, and fever; and as an analgesic, especially where there is an inflammatory component. Ibuprofen was developed by the research arm of Boots Group. more...

Home

Marinol

Marplan

Matulane

Maxair

Maxalt

Maxolon

MDMA

Medrol

Mobic

Modicon

Motrin

Mucinex

Muse

Mykacet

Mykinac

Myleran

Mylotarg

Mysoline

Phentermine

Clinical use

Low doses of ibuprofen (200 mg, and sometimes 400 mg) are available over the counter (OTC) in most countries. Ibuprofen has a dose-dependent duration of action of approximately 4–8 hours, which is longer than suggested by its short half-life. The recommended dose varies with body mass and indication. Generally, the oral dose is 200–400 mg (5–10 mg/kg in children) every 4–6 hours, up to a usual maximum daily dose of 800–1200 mg. Under medical direction, a maximum daily dose of 3200 mg may sometimes be used.

Indications

Approved clinical indications for ibuprofen include:

Rheumatoid arthritis (DMARDs should also be considered)
Osteoarthritis, ibuprofen can reduce pain and, if present, joint inflammation
Juvenile rheumatoid arthritis, alone or with corticosteroids
Morbus Bechterew (spondylitis ankylosans) together with corticosteroids
Rheumatic fever, together with antibiotic therapy
Acute gout attack, ibuprofen is not useful for chronic treatment
Primary dysmenorrhoea (ibuprofen proved superior to placebo and propoxyphen, and at least as effective as aspirin)
Fever
Pericarditis, chiefly after myocardial infarction, to reduce pain, fever and inflammation
Minor aches and pains such as toothache, backache, fever and pain associated with common flu, symptomatic relief of influenza, shingles, and postoperative pain
Sporting injuries and pain after mild to moderate trauma
Headache including mild to moderate migraine attack

Off-Label and investigational use

As with other NSAIDs, ibuprofen may be useful in the treatment of severe orthostatic hypotension (PMID 7041104)
In some studies, ibuprofen showed superior results compared to placebo in the prophylaxis of Alzheimer's disease, when given in low doses over a long time (PMID 16195368). Further studies are needed to confirm the results, before ibuprofen can be recommended for this indication.
Ibuprofen has been associated with a lower risk of Parkinson's disease, and may delay or prevent Parkinson's disease. Aspirin, other NSAIDs, and acetaminophen had no effect on the risk for Parkinson's (PMID 16240369). Further research is warranted before recommending ibuprofen for this use.

Ibuprofen lysine

In Europe and Australia, ibuprofen lysine (ibuprofenlysinat, the lysine salt of ibuprofen) is licensed for treatment of the same conditions as ibuprofen. Ibuprofen lysine is said to have a more rapid onset of action compared to base ibuprofen.

Mechanism of action

Ibuprofen is an NSAID which is believed to work through inhibition of cyclooxygenase (COX); thus inhibiting prostaglandin synthesis. As with other NSAIDs, ibuprofen inhibits platelet aggregation, but is not used therapeutically for this action since it is a minor and reversible effect.

Read more at Wikipedia.org

• [List your site here Free!]

Tests your doctor may not mention
From Essence, 11/1/05 by Kyissa Jemine

newborn

There are at least 28 genetic disorders, such as sickle-cell anemia, for which newborns can be tested. Yet according to the March of Dimes, 70 percent of babies don't receive all the screenings. "The general impression is that these diseases are rare and don't affect many kids," says Nancy S. Green, M.D., an associate professor of pediatrics at the Albert Einstein College of Medicine in New York City, "but they are not so rare." For example, sickle-cell anemia may afflict only one in 5,000 children, but when you multiply that figure by the number of births per state, Green notes, the condition becomes more common than you might think.

If not detected and treated early on, genetic disorders can lead to life-threatening infection, seizures, mental retardation and more. To make sure your newborn is properly screened, talk to your pediatrician, Green advises. (Log on to marchofdimes.com for a listing and definitions of the disorders.) A sample of your baby's blood can be taken by the hospital's staff within one to two days of birth. If your baby tests positive for any disease, discuss a treatment program with your doctor.

year one

your child has a temperature: when to worry

what's normal

Temperatures between 97[degrees]F and 100.5[degrees]F are typically no cause for concern. "A baby's body temperature in the late afternoon and early evening can be on the higher end and be perfectly normal," says Robert Adler, M.D., vice chair of the pediatrics department at the Childrens Hospital Los Angeles.

what's not

An above-normal temperature of 100.6[degrees]F and higher could mean the baby's fighting an infection. This, coupled with other warning signs--she's pulling at her ear or coughing; her urine smells different or bad; she's inconsolable, unusually sleepy, hard to reuse, or having difficulty breathing--may require a trip to the doctor. Describe the symptoms to your pediatrician and get her input.

HOW TO TAKE BABY'S TEMPERATURE

Do use a thermometer designed for children. Digital models are easier to read. Place the thermometer in your child's mouth or under his arm, or use it rectally.

Don't use a mercury thermometer. If it breaks, the mercury can contaminate the baby and her surroundings.

Do wait five to ten minutes before taking your child's temperature if she has been wearing lots of layers so her body can cool and you can get an accurate reading.

Do call your pediatrician to discuss your options if the temperature reading concerns you.

FOUND

A Kid-Friendly Thermometer

If it's hard to keep your little one from squirming while you take her temperature orally, rectally or under her arm, try out this new find: the Accu-Touch thermometer ($39.99; Toys "R" Us and Target stores nationwide). It's easy to use: Just press it against your child's forehead for seven seconds and wait for the beep.

FEVER no-no's

Don't give your child aspirin; Adler says it puts her at risk for a fatal liver disease. Instead, ask your doctor if she can take a dose of liquid children's Tylenol or Motrin.

Don't rub your baby down with rubbing alcohol, which can cool him too fast. In some cases, if absorbed, rubbing alcohol can cause neurological problems and even seizures.

Return to Motrin

Home

Contact

Resources

Exchange Links

ebay