Budesonide chemical structure
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Budesonide

Budesonide is a corticosteroid for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. Additionally, it is used for inflammatory bowel disease. It is marketed by AstraZeneca as a nasal inhalation with the brand name Rhinocort, as an oral inhalation with the brand name Pulmicort, and as an enema and a modified-release capsule with the brand name Entocort. It is also sold in combined with formoterol (Oxis) in a single inhaler, with the brand name Symbicort. more...

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Budesonide has a high first pass metabolism. It has efficacy in the terminal ileum and the right colon. It has a lower incidence of systemic manifestations than similar medications.

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Once-daily Pulmicort Turbuhaler aids asthma. (Children Previously on Multidose Therapy).(Brief Article) : An article from: Pediatric News $5.95 Adjustable inhalant dosing eases asthma flare-ups; tied to 57% fewer exacerbations.(Clinical Rounds) : An article from: Family Practice News $5.95
Cost-effectiveness analysis of early intervention with budesonide in mild persistent asthma. : An article from: Pediatrics $5.95

Prospective study comparing the efficacy of oral procaterol + low dose inhaled budesonide vs high dose inhaled budesonide alone in preventing exacerbations
PURPOSE: The aim of this study was to determine if addition of oral procaterol to low dose budesonide was comparable to high dose budesonide in preventing ...
Formoterol added to low-dose budesonide has no additional antiinflammatory effect in asthmatic patients
Study objective: Adding inhaled long-acting [[beta].sub.2]-agonists to a low dose of inhaled corticosteroids (ICSs) results in better asthma control ...
Effects of budesonide on overall 5-methylcytosine levels and specific methylation and messenger RNA expression of the insulin-like growth factor II gene
Abbreviations: IGF = insulin-like growth factor; SMC = 5-methylcytosine The effects of limited treatment with budesonide, an effective chemopreventive ...
Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate
Background: We evaluated the efficacy and safety of low-dose budesonide/formoterol, 80 [micro]g/4.5 [micro]g, bid in a single inhaler (Symbicort Turbuhaler; ...
Effect of inhaled budesonide on bronchial hyperresponsiveness in adolescents with clinical remission of asthma
Study objective: Many children with asthma go into long-term clinical remission at adolescence, but bronchial hyperresponsiveness (BHR) persists in some of these subjects. The regular use of inhale
Budesonide/Formoterol Combination Therapy as Both Maintenance and Reliever Medication in Asthma
Asthma control is improved by combining inhaled corticosteroids with long-acting β^sub 2^-agonists. However, fluctuating asthma control still occurs. We hypothesized that in patients receiving low ma
Is budesonide or nedocromil superior in the long-term management of mild to moderate asthma in children?
Childhood Asthma Management Program Research Group. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med 2000; 343:1054-63.
Anaphylactic-like reaction associated with oral budesonide - Drug Points
Anaphylactic-like reaction associated with oral budesonide Corticosteroids have antiallergic properties, which should reduce the likelihood of anaphylactic-like ...

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