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Alpidem

Alpidem is a prescription drug used for the treatment of moderate to severe anxiety. Alpidem, a fairly new drug, is not in wide use. Alpidem, in pure form, is only available generically, but is an additonal substance in a few prescription anxiolytic drugs. Alpidem acts selectively on the omega 1 (BZ1) receptor subtype, a benzodiazepine receptor. However, alpidem is not considered of the benzodiazepine class, but is rather a imidazopyridine. Alpidem is a close relative of zolpidem, but does not possess zolpidem's sedative property. more...

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Uses

Alpidem is generally prescribed to patients with moderate to severe anxiety. Most of these patients have exhibited either sensitivity or resistance to benzodiazepine therapy, and therefore switched to a non-benzodiazepine medication. See also anxiolytic. Alpidem does not produce significant, if any, sedative or hypnotic action. Alpidem is also used as an anticonvulsant at higher doses.

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Imidazopyridines in Anxiety Disorders: A Novel Experimental and Therapeutic Approach (L E R S Monograph Series) $83.00

Hepatotoxicity associated with zolpidem treatment
Zolpidem is a hypnotic drug of the imidazopyridine group. Another imidazopyridine, alpidem, has been withdrawn from the market because of its hepatotoxicity.[1 ...

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