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Avodart

Avodart (Dutasteride) is a drug most commonly used for reduction of the prostate. more...

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Classification and Method of Action

Avodart belongs to a class of drugs called 5-alpha-reductase inhibitors, which inhibit the conversion of testosterone into dihydrotestosterone (DHT). Propecia (finasteride) also belongs to this group. However, Avodart is more effective and quicker-acting than Propecia because it inhibits both forms of 5-alpha-reductase, whereas Propecia inhibits one.

Uses

While Avodart is officially approved, and most commonly used, to treat enlargement of the prostate gland, it may also be used to treat male pattern baldness. While clinical trials for Avodart as a hair loss drug were called off in late 2002, it can still be prescribed for "off-label" purposes by physicians, and an increasing number are willing to do so.

The reason the trials were called off is not outwardly known. However, industry sources speculate that Avodart would have been seen as too similar to Propecia to have proved profitable as a hair loss treatment.

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