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Altace

Ramipril (marketed as TritaceĀ® or AltaceĀ®) is an angiotensin converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. ACE inhibitors lower the production of Angiotensin II, therefore relaxing arterial muscles while at the same time enlarging the arteries, allowing the heart to pump blood easier, and increasing blood flow due to more blood being pumped into and through bigger passageways. more...

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Ramipril is a prodrug and is converted to the active metabolite ramiprilat by liver esterase enzymes. Ramiprilat is mostly excreted by the kidneys. The half-life of ramiprilat is variable (3 - 16 hours), and is prolonged by heart and liver failure, as well as kidney failure.

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King Pharmaceuticals reports that Altace® - market share information - Brief Article
From Drug Cost Management Report, 6/1/02

* King Pharmaceuticals reports that Altace[R] (ramipril) has overtaken its nearest competitor in the ACE inhibitor market. The company says IMS America weekly prescription data for the week ending May 3 shows Altace has a 21.3% market share among cardiologists. Altace is approved for treatment of hypertension and congestive heart failure after heart attack, and also is approved to reduce the risk of stroke, myocardial infarction and death from cardiovascular causes in patients over age 55 with certain risk factors. Information: James Green, (423) 989-8125.

COPYRIGHT 2002 Atlantic Information Services, Inc.
COPYRIGHT 2003 Gale Group

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