Trenbolone chemical structureFinaplix Gold, Manufactured by Valopharm
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Trenbolone

Trenbolone is an anabolic steroid used by veterinarians on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is not used in an unrefined form, but is rather administered as trenbolone acetate (Finaplix Gold from Valopharm USA, TREMBLONA QV75from Quality Vet, Mexico), or trenbolone cyclohexylmethylcarbonate (Parabolan from Laboratoires NEGMA until 1997). Trenbolone is then produced as a metabolite by the reaction of these compounds with the androgen receptor. more...

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No trenbolone compounds have been approved by the FDA for human use, due to a lack of clinical applications and considerable negative side-effects. It is classified as a Schedule III drug under the Controlled Substances Act. However, bodybuilders have been known to use the drug illicitly in order to increase body mass more effectively than by weight training alone.

Trenbolone compounds have a binding affinity for the androgen receptor three times as high as that of testosterone. Once metabolised, the drugs have the effect of increasing nitrogen uptake by muscles, leading to an increase in the rate of protein synthesis. It also has the secondary effects of stimulating appetite, reducing the amount of fat being deposited in the body, and decreasing the rate of catabolism. Trenbolone has proven popular with anabolic steroid users as it is not metabolised by aromatase or 5α-reductase into estrogenic compounds such as estradiol, or into DHT. This means that it also does not cause any water retention normally associated with highly androgenic steroidal compounds like testosterone or methandrostenolone. It is also loved by many for the dramatic strength increases commonly experienced with it. Some short-term side effects include insomnia, high blood pressure and increased aggression and libido. However, since women will suffer virilization effects even at small doses, this drug should not be taken by a female. The use of the drug over extended periods of time can lead to kidney damage and sterility for both sexes. The kidney toxicity has not yet been proven.

A normal body-building dosage can range from 200mgs/week up to 500 plus mgs/week. Due to it's relatively short metabolic half-life, dosages should commonly be split into injections at least once every two days.

Trenbolone cyclohexymethylcarbonate has effects identical to those of trenbolone acetate as they produce the same active metabolite, but has a significantly longer elimination half-life: up to a week rather than one or two days.

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Effects of restricted feeding, low-energy diet, and implantation of trenbolone acetate plus estradiol on growth, carcass traits, and circulating concentrations ... : An article from: Journal of Animal Science $20.00 Effects of implant regimens (trenbolone acetate-estradiol administered alone or in combination with zeranol) and vitamin D(3) on fresh beef color and quality ... : An article from: Journal of Animal Science $20.00
Body weight and tissue gain in lambs fed an all-concentrate diet and implanted with trenbolone acetate or grazed on alfalfa : An article from: Journal of Animal Science $20.00

The fate of trenbolone acetate and melengestrol acetate after application as growth promoters in cattle: environmental studies - Articles
The steroids trenbolone acetate (TbA) and melengestrol acetate (MGA) are licensed as growth promoters for farm animals in several meat-exporting countries.
Effects of Vitamin A and Restricted Intake on Performance, Carcass Characteristics, and Serum Retinol Status in Angus × Simmental Feedlot Cattle
Abstract Three feedlot experiments examined the effects of vitamin A (VA) on marbling and serum retinal (ROL) in Angus × Simmental cattle. Diets contained ...
CASE STUDY: Effects of Implant Programs on Buller Incidence, Feedlot Performance, and Carcass Characteristics of Yearling Steers1
Abstract English and English × Continental crossbred steers (272 steers per pen; 4 pens per treatment) were used in a randomized complete block design ...
Effects of Feed Intake Restriction on Performance and Carcass Characteristics of Finishing Beef Steers1,2
Abstract Crossbred steers (n = 264, 311 ± 1.6 kg initial BW) were blocked by BW, randomly assigned to one of four treatments (28 pens, 7 pens per treatment), ...
CASE STUDY: Effects of Delaying Implant and Programmed Rate of Gain on Performance and Carcass Characteristics of Yearling Beef Steers1
Abstract Ninety-six steers (average BW = 335 ± 36 kg) were allotted in a completely randomized design with a 2 × 2 factorial arrangement of treatments.
Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow - Research
Over the last decade, research has examined the endocrine-disrupting action of various environmental pollutants, including hormones, pharmaceuticals, ...
Androgenic and estrogenic activity in water bodies receiving cattle feedlot effluent in Eastern Nebraska, USA - Research
Studies reveal that surface waters worldwide are contaminated with hormonally active agents, many released from sewage treatment plants. Another potential ...
OECD validation of the Hershberger assay in Japan: phase 2 dose response of methyltestosterone, vinclozolin, and p,p'-DDE - Research
The Organisation for Economic Co-operation and Development has initiated the development of new guidelines for the screening and testing of potential ...

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