Find information on thousands of medical conditions and prescription drugs.

Ceftriaxone

Ceftriaxone (trade name Rocephin®) is a third-generation cephalosporin antibiotic. Ceftriaxone is frequently used in combination with azithromycin for the treatment of community-acquired pneumonia. It is also a choice drug for treatment of bacterial meningitis. Rocephin is manufactured by Hoffmann-La Roche pharmaceuticals. The usual starting dose is 2 grams IV daily. There need not be any adjustment in dosing for renal or liver function. more...

Home
Diseases
Medicines
A
B
C
Cabergoline
Caduet
Cafergot
Caffeine
Calan
Calciparine
Calcitonin
Calcitriol
Calcium folinate
Campath
Camptosar
Camptosar
Cancidas
Candesartan
Cannabinol
Capecitabine
Capoten
Captohexal
Captopril
Carbachol
Carbadox
Carbamazepine
Carbatrol
Carbenicillin
Carbidopa
Carbimazole
Carboplatin
Cardinorm
Cardiolite
Cardizem
Cardura
Carfentanil
Carisoprodol
Carnitine
Carvedilol
Casodex
Cataflam
Catapres
Cathine
Cathinone
Caverject
Ceclor
Cefacetrile
Cefaclor
Cefaclor
Cefadroxil
Cefazolin
Cefepime
Cefixime
Cefotan
Cefotaxime
Cefotetan
Cefpodoxime
Cefprozil
Ceftazidime
Ceftriaxone
Ceftriaxone
Cefuroxime
Cefuroxime
Cefzil
Celebrex
Celexa
Cellcept
Cephalexin
Cerebyx
Cerivastatin
Cerumenex
Cetirizine
Cetrimide
Chenodeoxycholic acid
Chloralose
Chlorambucil
Chloramphenicol
Chlordiazepoxide
Chlorhexidine
Chloropyramine
Chloroquine
Chloroxylenol
Chlorphenamine
Chlorpromazine
Chlorpropamide
Chlorprothixene
Chlortalidone
Chlortetracycline
Cholac
Cholybar
Choriogonadotropin alfa
Chorionic gonadotropin
Chymotrypsin
Cialis
Ciclopirox
Cicloral
Ciclosporin
Cidofovir
Ciglitazone
Cilastatin
Cilostazol
Cimehexal
Cimetidine
Cinchophen
Cinnarizine
Cipro
Ciprofloxacin
Cisapride
Cisplatin
Citalopram
Citicoline
Cladribine
Clamoxyquine
Clarinex
Clarithromycin
Claritin
Clavulanic acid
Clemastine
Clenbuterol
Climara
Clindamycin
Clioquinol
Clobazam
Clobetasol
Clofazimine
Clomhexal
Clomid
Clomifene
Clomipramine
Clonazepam
Clonidine
Clopidogrel
Clotrimazole
Cloxacillin
Clozapine
Clozaril
Cocarboxylase
Cogentin
Colistin
Colyte
Combivent
Commit
Compazine
Concerta
Copaxone
Cordarone
Coreg
Corgard
Corticotropin
Cortisone
Cotinine
Cotrim
Coumadin
Cozaar
Crestor
Crospovidone
Cuprimine
Cyanocobalamin
Cyclessa
Cyclizine
Cyclobenzaprine
Cyclopentolate
Cyclophosphamide
Cyclopropane
Cylert
Cyproterone
Cystagon
Cysteine
Cytarabine
Cytotec
Cytovene
Isotretinoin
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z

It is one of the newest antibiotics on the market and is particularly effective against respiratory infections.

Ceftriaxone can be used to cover gram-positive organisms, but this drug does not cover Staphylococcus Aureus. For this organism, nafcillin is best to use.

Side Effects include:

  • diarrhea
  • stomach pain
  • upset stomach
  • vomiting

Read more at Wikipedia.org


[List your site here Free!]


Single-Dose Ceftriaxone for Acute Otitis Media
From American Family Physician, 10/1/99 by Richard Sadovsky

Acute otitis media in children frequently requires antibiotic prescriptions. Although acute otitis media usually resolves spontaneously, antibiotic treatment is prescribed to prevent complications such as mastoiditis or meningitis. The antibiotic will also decrease the chance of hearing loss and permanent damage to the middle ear and will relieve symptoms. Resistance to pathogens that cause acute otitis media, including Streptococcus pneumoniae-resistance to penicillins and macrolide antibiotics, is occurring in many countries. Alternative therapies have included ceftriaxone, a third-generation cephalosporin with a spectrum of antibacterial activity, including most of the common pathogens of acute otitis media. Cohen and associates compared the efficacy and safety of a single intramuscular dose of ceftriaxone with a 10-day course of oral amoxicillin-clavulanate potassium treatment in infants and children with acute otitis media.

Children between the ages of four months and 30 months with acute otitis media (indicated by the presence of an effusion and marked redness or bulging, or moderate redness and bulging associated with fever, otalgia, irritability or any combination of these symptoms) were included in the study group. Children who had recently taken antibiotics or who had a known hypersensitivity to beta-lactam antibiotics or a severe underlying disease were excluded from participation. Study subjects were randomly assigned to receive either a single intramuscular dose of ceftriaxone, 50 mg per kg, or amoxicillin in a dosage of 80 mg per kg per day and clavulanate potassium in a dosage of 10 mg per kg in three divided doses daily for 10 days. Symptoms were followed, as were post-treatment changes in the presence of S. pneumonia, Haemophilus influenzae and Moraxella catarrhalis in the nasopharynx.

Clinical response was similar in both groups. There was no evidence that treatment with ceftriaxone contributed more to the emergence of resistance than 10 days of treatment with an oral antibiotic. Adverse effects, including gastrointestinal symptoms, were significantly higher in the amoxicillin-clavulanate potassium group.

The authors conclude that in young children, the population less likely to have spontaneous recovery after acute otitis media, treatment with a single dose of ceftriaxone is clinically equivalent to 10 days of treatment with amoxicillin-clavulanate potassium. Ceftriaxone therapy is well-suited for use in children who have compliance problems, decreased oral absorption because of vomiting, high fever or possible concurrent bacteremias.

RICHARD SADOVSKY, M.D.

Cohen R, et al. One dose ceftriaxone vs. ten days of amoxicillin-clavulanate therapy for acute otitis media: clinical efficacy and change in nasopharyngeal flora. Pediatr Infect Dis J May 1999;18:403-9.

COPYRIGHT 1999 American Academy of Family Physicians
COPYRIGHT 2000 Gale Group

Return to Ceftriaxone
Home Contact Resources Exchange Links ebay