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Cidofovir

Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA synthesis. more...

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Cidofovir demonstrated a statistically significant effect in delaying the progression of CMV retinitis lesions in newly diagnosed patients, as well as in previously treated patients who had failed other therapies. Maintenance therapy with cidofovir involves an infusion only once every two weeks, making it a convenient treatment option. Because dosing is relatively infrequent, a permanent catheter is not necessary for infusions.

Cidofovir has also been investigated as a treatment for progressive multifocal leukoencephalopathy, but as of 2005 studies are inconclusive.

Cidofovir was developed by Gilead Sciences and is marketed with the brand name Vistide by Gilead in the USA, and by Pfizer elsewhere.

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	Cidofovir treatment of progressive multifocal leukoencephalopathy in a patient receiving highly active antiretroviral therapy : An article from: Mayo Clinic Proceedings $20.00	Topical 1% cidofovir healed basal cell carcinoma: small but promising series. (Dermatologic Therapy). : An article from: Skin & Allergy News $5.95

	Case of Progressive Dysplasia Concomitant With Intralesional Cidofovir Administration for Recurrent Respiratory Papillomatosis : An article from: The Annals of Otology, Rhinology & Laryngology $10.00


Clinical clearance of basal cell carcinoma with topical cidofovir - Washington Whispers - Brief Article In this case report, four patients are described with basal cell carcinomas (BCC) treated with 1% topical cidofovir. Cidofovir is a purine nucleotide ... From Journal of Drugs in Dermatology, 4/1/03

Successful Treatment of Juvenile Laryngeal Papillomatosis-Related Multicystic Lung Disease With Cidofovir - ) Case Report and Review of the Literature Cidofovir, a nucleoside analog antiviral agent, has been used with moderate success in the treatment of juvenile ... From CHEST, 10/1/00 by David R. Dancey

Intralesional cidofovir for recurrent laryngeal papillomas: Preliminary report Abstract This is a preliminary report of an ongoing study to test the efficacy of intralesional injections of the antiviral drug cidofovir in adults ... From Ear, Nose & Throat Journal, 4/1/00 by William R. Wilson

Disseminated recurrent respiratory papillomatosis in an adult male with sarcoidosis INTRODUCTION: Recurrent respiratory papillomatosis (RRP) is the most benign laryngeal neoplasm in children, however it is less common in adults. The ... From CHEST, 10/1/05 by Dominic J. Valentino, III

Smallpox vaccine: contraindications, administration, and adverse reactions Since the terrorist attacks of September 11, 2001, and the anthrax exposures in the following weeks, concern that smallpox could be used as a biologic ... From American Family Physician, 9/1/03 by Douglas M. Maurer

Visualization of the hyoid bone with laryngeal endoscopy A 51-year-old businessman with a history of recurrent laryngeal papillomatosis presented to our office for an evaluation. He had undergone numerous excisions and photodynamic therapy by other otola From Ear, Nose & Throat Journal, 1/1/05 by Adam D. Rubin

Polyomavirus in a Lung Transplant Patient A 51-year-old Asian woman with a history of systemic scleroderma underwent bilateral lung transplantation for end-stage lung disease. She was then put ... From Archives of Pathology & Laboratory Medicine, 12/1/04 by Jani, Jigna C

New drug for AIDS-related eye infection - cytomegalovirus retinitis; cidofovir - Brief Article A new drug is available for treating cytomegalovirus (CMV) retinitis, a potentially severe eye infection that can lead to blindness. While other therapies ... From FDA Consumer, 10/1/96

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