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Ceftriaxone

Ceftriaxone (trade name Rocephin®) is a third-generation cephalosporin antibiotic. Ceftriaxone is frequently used in combination with azithromycin for the treatment of community-acquired pneumonia. It is also a choice drug for treatment of bacterial meningitis. Rocephin is manufactured by Hoffmann-La Roche pharmaceuticals. The usual starting dose is 2 grams IV daily. There need not be any adjustment in dosing for renal or liver function. more...

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It is one of the newest antibiotics on the market and is particularly effective against respiratory infections.

Ceftriaxone can be used to cover gram-positive organisms, but this drug does not cover Staphylococcus Aureus. For this organism, nafcillin is best to use.

Side Effects include:

diarrhea
stomach pain
upset stomach
vomiting

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Ceftriaxone vs. cefotaxime in abdominal surgery - Tips from Other Journals The third-generation cephalosporin antibiotics ceftriaxone and cefotaxime are widely used for prophylaxis in abdominal surgery. Both are active against ... From American Family Physician, 6/1/03 by Anne D. Walling

Once-daily cefazolin vs. ceftriaxone for cellulitis - Tips from Other Journals Many of the respiratory, urinary, and skin infections that were traditionally treated in the hospital setting are now managed with home-based care or ... From American Family Physician, 9/15/02 by Bill Zepf

Frozen premixed ceftriaxone Ceftriaxone injection (1 g/50 mL and 2 g/50 mL) is now packaged in single-dose plastic containers. The premixed frozen drug is ready to use. Ceftriaxone ... From OB/GYN News, 11/1/05

Cost-effectiveness of Gatifloxacin vs Ceftriaxone With a Macrolide for the Treatment of Community-Acquired Pneumonia - .Abstract - ) Study objective: To determine the cost-effectiveness of sequential IV to oral gatifloxacin therapy vs IV ceftriaxone with or without IV erythromycin ... From CHEST, 5/1/01 by Linda D. Dresser

A Case of Acute Hemolysis After Ceftriaxone: Immune Complex Mechanism Demonstrated by Flow Cytometry An immune complex mechanism for ceftriaxone sodiuminduced severe autoimmune hemolytic anemia has previously been demonstrated using routine blood bank ... From Archives of Pathology & Laboratory Medicine, 8/1/04 by Kakaiya, Ram

Levofloxacin Vs. Ceftriaxone And Erythromycin Followed By Clarithromycin And Amoxicillin/Clavulanate In Serious Community-Acquired Pneumonia - Abstract James B Kahn, MD(*); Barbara A Wiesinger BSN; Margaret P Oross, BSN, MHSA and William H Olson, PhD. Ortho-McNeil Pharmaceutical, Raritan, NJ. PURPOSE: ... From CHEST, 10/1/00 by James B Kahn

Is Ceftriaxone Effective for Staphylococcal Osteomyelitis? Intravenous agents commonly used in the treatment of staphylococcal osteomyelitis include nafcillin, vancomycin and cefazolin. Although effective, they ... From American Family Physician, 4/15/00 by Jeffrey T. Kirchner

Single-Dose Ceftriaxone for Acute Otitis Media Acute otitis media in children frequently requires antibiotic prescriptions. Although acute otitis media usually resolves spontaneously, antibiotic treatment is prescribed to prevent complications From American Family Physician, 10/1/99 by Richard Sadovsky

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