Chlorhexidine (free base) structure
Find information on thousands of medical conditions and prescription drugs.

Chlorhexidine

Chlorhexidine Gluconate is an antiseptic used as an active ingredient in mouthwash designed to kill dental plaque and other oral bacteria. In some countries it is available by prescription only. It is sometimes marketed under the brand names Peridex, Periochip, Periogard Oral Rinse or in the UK Corsodyl or Chlorohex. Chlorhexidine Gluconate-based products are usually utilized to combat or prevent gum diseases such as gingivitis. more...

Home
Diseases
Medicines
A
B
C
Cabergoline
Caduet
Cafergot
Caffeine
Calan
Calciparine
Calcitonin
Calcitriol
Calcium folinate
Campath
Camptosar
Camptosar
Cancidas
Candesartan
Cannabinol
Capecitabine
Capoten
Captohexal
Captopril
Carbachol
Carbadox
Carbamazepine
Carbatrol
Carbenicillin
Carbidopa
Carbimazole
Carboplatin
Cardinorm
Cardiolite
Cardizem
Cardura
Carfentanil
Carisoprodol
Carnitine
Carvedilol
Casodex
Cataflam
Catapres
Cathine
Cathinone
Caverject
Ceclor
Cefacetrile
Cefaclor
Cefaclor
Cefadroxil
Cefazolin
Cefepime
Cefixime
Cefotan
Cefotaxime
Cefotetan
Cefpodoxime
Cefprozil
Ceftazidime
Ceftriaxone
Ceftriaxone
Cefuroxime
Cefuroxime
Cefzil
Celebrex
Celexa
Cellcept
Cephalexin
Cerebyx
Cerivastatin
Cerumenex
Cetirizine
Cetrimide
Chenodeoxycholic acid
Chloralose
Chlorambucil
Chloramphenicol
Chlordiazepoxide
Chlorhexidine
Chloropyramine
Chloroquine
Chloroxylenol
Chlorphenamine
Chlorpromazine
Chlorpropamide
Chlorprothixene
Chlortalidone
Chlortetracycline
Cholac
Cholybar
Choriogonadotropin alfa
Chorionic gonadotropin
Chymotrypsin
Cialis
Ciclopirox
Cicloral
Ciclosporin
Cidofovir
Ciglitazone
Cilastatin
Cilostazol
Cimehexal
Cimetidine
Cinchophen
Cinnarizine
Cipro
Ciprofloxacin
Cisapride
Cisplatin
Citalopram
Citicoline
Cladribine
Clamoxyquine
Clarinex
Clarithromycin
Claritin
Clavulanic acid
Clemastine
Clenbuterol
Climara
Clindamycin
Clioquinol
Clobazam
Clobetasol
Clofazimine
Clomhexal
Clomid
Clomifene
Clomipramine
Clonazepam
Clonidine
Clopidogrel
Clotrimazole
Cloxacillin
Clozapine
Clozaril
Cocarboxylase
Cogentin
Colistin
Colyte
Combivent
Commit
Compazine
Concerta
Copaxone
Cordarone
Coreg
Corgard
Corticotropin
Cortisone
Cotinine
Cotrim
Coumadin
Cozaar
Crestor
Crospovidone
Cuprimine
Cyanocobalamin
Cyclessa
Cyclizine
Cyclobenzaprine
Cyclopentolate
Cyclophosphamide
Cyclopropane
Cylert
Cyproterone
Cystagon
Cysteine
Cytarabine
Cytotec
Cytovene
Isotretinoin
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z

Chlorhexidine Gluconate is also used in non-dental applications, most notably under the brand name Hibiclens, to combat microbes. It is used for general skin cleansing, a surgical scrub and a pre-operative skin preparation. Due to other chemicals listed as inactive ingredients, Hibiclens is not suitable for use as mouthwash.

Known to be deactivated by fluoride, Chlorhexidine Gluconate mouth rinses should be taken at least 30 minutes after using fluoridated oral products (e.g, toothpaste and mouthwash). For best effectiveness, food, drink, and mouth rinses should be avoided for at least one hour after use. However, mouthwashes formulations containing both chlorhexidine digluconate and fluoride have been found to be effective.

Read more at Wikipedia.org


[List your site here Free!]


Chlorhexidine bests povidone iodine in small study
From OB/GYN News, 10/1/04 by Doug Brunk

SAN DIEGO -- Chlorhexidine was more effective than povidone iodine in sterilizing the vagina before hysterectomy in a small, randomized study.

"We can't say that using chlorhexidine would lead to a reduction in infections following vaginal hysterectomy, but I think we can say that it is more effective than povidone iodine in decreasing bacterial colony counts," Dr. Patrick Culligan said at the joint annual meeting of the American Urogynecologic Society and the Society of Gynecologic Surgeons.

"By my way of thinking, this interventional change would be no more expensive and no more time consuming, and it seems to make the vagina cleaner for surgery," Dr. Culligan said.

For the study, he and his associates randomized 50 women who underwent vaginal hysterectomy between October 2002 and September 2003 to receive a surgical scrub with either povidone iodine or chlorhexidine. Standard prophylactic techniques were used for both groups, including preoperative intravenous antibiotics, said Dr. Culligan of the division of urogynecology at the University of Louisville (Ky.) Health Sciences Center.

Investigators obtained aerobic and anaerobic bacterial cultures of the vaginal field from both groups preoperatively, 30 minutes after the surgical scrub, and hourly thereafter for each patient. Specimens were defined as contaminated if the total bacterial colony counts were at least 5,000 colony-forming units (CFU)/mL.

The mean preoperative colony count for the povidone iodine group was significantly higher, compared with the chlorhexidine group (211,975 vs. 172,296 CFU/mL). Thirty minutes after the surgical scrub, 63% of culture specimens from the povidone iodine group and 22% of the chlorhexidine group were contaminated. Ninety minutes after the surgical scrub that trend persisted, with 36% of the povidone iodine group and 14% of the chlorhexidine group classified as contaminated.

Limitations of the study include the fact that the clinical relevance of the end point of bacterial colony counts "may be in question," Dr. Culligan said. "You may ask, 'why wouldn't you just use infections as your end point?' We looked into that and [determined that] a study powered to detect the reduction of infection from say, 6% to 3%, would require greater than 800 patients in each arm. That's a tough study to do."

BY DOUG BRUNK

San Diego Bureau

COPYRIGHT 2004 International Medical News Group
COPYRIGHT 2004 Gale Group

Return to Chlorhexidine
Home Contact Resources Exchange Links ebay