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Cyclessa

Oral contraceptives come in a variety of formulations. The main division is between combined oral contraceptive pills, containing both estrogen and progesterone, and progesterone only pills (mini-pills). Combined oral contraceptive pills also come in varying types, including varying doses of estrogen, and whether the dose of estrogen or progesterone changes from week to week. more...

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Combined oral contraceptive pills

All contain the estrogen ethinyl estradiol, although in varying amounts, and one of a number of different progesterones. They are taken for 21 days with then a 7 day gap during which a withdrawal bleed (often, but incorrectly, referred to as a menstrual period) occurs. These differ in the amount of estrogen given, and whether they are monophasic (only one dose of estrogen and progesterone during the 21 days) or multiphasic (varying doses).

Monophasic

These are given as 21 tablets of estrogen and progesterone, followed by 7 tablets of placebo. Different formulations contain different amounts of estrogen and progesterone:

  • 20 mcg estrogen
    • 0.1 mg levonorgestrel (Alesse®, Levline®)
    • 1 mg norethindrone acetate (Loestrin 1/20®Fe)
  • 30 mcg estrogen
    • 0.15 mg levonorgestrel (Levlen®, Levora®, Nordette®)
    • 0.3 mg norgestrel (Lo-Ovral®)
    • 0.15 mg desogestrel (Desogen®, Organon; Ortho-Cept®, Ortho-McNeil)
    • 1.5 mg norethindrone acetate (Loestrin® 1.5/30)
    • 3.0 mg drospirenone (Yasmin®)
  • 35 mcg estrogen
    • 0.25 mg norgestimate (Ortho-Cyclen®)
    • 0.4 mg norethindrone (Ovcon-35®, Warner Chilcott)
    • 0.5 mg norethindrone (Modicon®, Brevicon®)
    • 1 mg norethindrone (Ortho-Novum 1/35®, Necon®, Norethin®, Norinyl 1/35®)
    • 1 mg ethynodiol diacetate (Demulen 1/35®, Zovia 1/35E®)
  • 50 mcg estrogen
    • 0.4 mg norethindrone (Ovcon-50®, Warner Chilcott))
    • 1 mg norethindrone (Necon 1/50®, Norinyl 1/50®, Ortho-Novum 1/50®, Ovcon-50®)
    • 0.5 mg norgestrel (Ovral®)
    • 1 mg ethynodiol diacetate (Demulen 1/50®, Zovia 1/50E®)

Multiphasic

  • Desogestrel 0.15 mg and ethinyl estradiol 0.02 mg x 14 tablets, followed by ethynil estradiol 0.01 mg x 2 tablets, followed by 5 tablets of placebo (Kariva®, Barr Laboratories; Mircette®, Organon)
  • Desogestrel 0.1 mg ethynil estradiol 0.025 mg x 7 tablets, followed by desogestrel 0.125 mg and ethynil estradiol 0.025 mg x 7 tablets, followed by desogestrel 0.15 mg and ethynil estradiol 0.025 mg x 7 tablets, followed by 7 tablets of ferric oxide (Cyclessa®, Organon; Velivet®, Barr Laboratories)
  • Norethindrone 0.5 mg and ethinyl estradiol 0.035 mg x 7 tablets, followed by 0.75 mg of norethindrone and 0.035 mg of ethinyl estradiol x 7 tablets, followed by 1 mg of norethindrone and 0.035 of ethinyl estradiol, followed by 7 tablets of placebo (Ortho-Novum 7/7/7®)
  • Norethindrone 0.5 mg and 0.035 mg of ethinyl estradiol x 10 tablets, followed by 1 mg norethindrone and 0.035 ethinyl estradiol x 11 tablets, followed by 7 tablets of placebo (Ortho-Novum 10/11®)

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CostDoctor and Organon To Help Doctors Optimize `The Business of Medicine' With Unique Software; CostDoctor Enters Strategic Marketing Agreement With Organon
From Business Wire, 1/23/02

Business Editors & Health/Medical/High-Tech Writers

AUSTIN, Texas--(BW HealthWire)--Jan. 23, 2002

CostDoctor Inc., the leader in activity-based costing software for physicians, today announced the signing of a strategic marketing agreement with Organon Inc.

Organon Inc.'s sales force will provide 20,000 obstetricians and gynecologists across the United States with the innovative cost analysis software designed to help medical professionals maximize office performance through in-depth analysis and practical applications.

"Our collaboration with Organon is extremely exciting, because physicians will now have a tool that will take their cost and margin analysis to a new and deeper level," said Dr. Kaylen Silverberg, Chairman and Founder of CostDoctor Inc. "The CostDoctor software will allow physicians to meet the dual challenges of increasing costs and declining reimbursements. By providing physicians with a tool to better manage their costs, better evaluate their reimbursements and ultimately better preserve the profitability of their practice, physicians can focus on the most important goal of all, the health and well-being of their patients."

"As a global leader in pharmaceutical innovation, Organon has long since demonstrated its commitment to women's health. We have always placed a great emphasis on strategic research alliances in terms of drug research and development," said Hans Radder, President, Organon Inc. "But in today's environment it is vitally important to understand all of the factors critical to delivering the very best health care. We believe that our relationship with CostDoctor further supports our commitment to support the medical community with products and services for better health care."

Under the terms of the agreement, Organon's field sales force will distribute an introductory version of the software to obstetricians and gynecologists. CostDoctor software can be used to uncover fundamental information that is critical to maximizing office efficiencies and uncover the true costs associated with providing quality medicine in a challenging and evolving healthcare environment. CostDoctor will provide customer service and technical support for participating practices.

About CostDoctor Inc.

CostDoctor Inc. delivers software and services that enable physicians to realize their full profit-potential. CostDoctor's proprietary software empowers physicians with the information necessary to maximize practice efficiency and uncover the true costs of doing business. Through CostDoctor, physicians can identify their actual costs for every procedure (CPT code), treatment and medical service. Physicians can map these costs to each of their reimbursement plans, thus revealing their unique profit structure. The CostDoctor software gives physicians a greater sense of control over their costs, their reimbursements and ultimately their business. CostDoctor Inc. is a software and services company. Based in Austin, Texas, CostDoctor is privately held and is funded by Castletop Capital. www.costdoctor.com

About Organon Inc.

Organon provides comprehensive service and support programs to health care professionals across specialties including continuing medical education. In the U.S., Organon focuses on three critical areas of women's health: contraception, fertility and hormone replacement therapy/osteoporosis. It is one of the few international companies conducting research into new fertility drugs and contraceptives.

Organon Inc. of West Orange, N.J. is the U.S. affiliate of N.V. Organon, a renowned international ethical pharmaceutical company. Organon maintains a strong commitment to health care, conducting research in the areas of psychiatry, contraception, fertility, anesthesiology, thrombosis, immunology, osteoporosis prevention and treatment of post-menopausal symptoms. Organon Inc.'s contraceptive products include Mircette(tm) (desogestrel/ethinyl estradiol and ethinyl estradiol) Tablets, Cyclessa(tm) (desogestrel/ethinyl estradiol) Tablets and NuvaRing(R)(etonogestrel/ethinyl estradiol vaginal ring).

About Akzo Nobel

Organon is one of the business units of Akzo Nobel N.V. Headquartered in The Netherlands, Akzo Nobel N.V. is a market-driven and technology-based company, serving customers throughout the world with health care products, coatings and chemicals. The company employs 68,000 people and has activities in more than 70 countries. www.organoninc.com

For more information, please visit www.costdoctor.com or www.organoninc.com.

COPYRIGHT 2002 Business Wire
COPYRIGHT 2002 Gale Group

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